Sachdeva Laboratory

 

OUR RESEARCH

Our team works in a multidisciplinary approach using Nanotechnology to combat devastating diseases like Breast and lung cancer. One of the emphases here is overcoming lung cancer mutations induced after using various Tyrosine kinase inhibitors.  Our laboratory uses various novel compounds that act as chemosensitizers and help overcome resistance in lung and breast cancers.  We are also using exosomes as markers of tumor progression, enabling diagnosis and tumor progression as a liquid biopsy.  Another emphasis is to use 3D printing approaches to develop tumor scaffolds and conduct cytotoxicity assays using 3D printed co-cultures of tumor cells and fibroblasts. Apart from this, our team is also printing Cornea using various bioinks.

MISSION


Our team’s mission is to use Nanotechnology and 3D printing approaches to develop innovations in diagnosing and treating diseases like lung and breast cancer, corneal wounds, and obesity.

VISION

Take up an idea – think of it, dream of it, live on that idea. Let the brain, muscles, nerves, every part of your body, be full of that idea. This is the way to success.

FACILITIES 

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3D Printer
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Cell Culture Facility
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Differential Scanning Calorimeter (DSC)
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Dissolution Apparatus
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FTIR
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Fluorescent Microscope
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Franz Diffusion Setup
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Gel Documentation
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Holt Melt Extruder (HME)
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Nano DeBee
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Particle Sizer & Zeta Potential
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Spray Dryer

THE SACHDEVA LABORATORY 

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BIOSKETCH                       Mandip S. Sachdeva, Ph.D.

Professor of Pharmaceutical Sciences, Fulbright Fellow, AAPS Fellow Editor in Chief, Critical Reviews in Therapeutic Drug Carrier Systems

Ph.D. (1986-89) Dalhousie University, Halifax, NS, Canada.
M.S. (1984-86) Dalhousie University, Halifax, NS, Canada.
M.Pharm (1978-80) – Punjab University, Chandigarh, India
B.Pharm (Hon,1975-78) – Punjab University, Chandigarh, India
  1. December 1980-March 1982: Production Supervisor, Ranbaxy Labs, Okhla, New Delhi.
  2. March 1982 - September 1984: Assistant Manager, Manufacturing, Alembic Chemical Work, Baroda, India.
  3. July 1989 - September 1993: Group Leader, Drug Targeting, SynPhar Labs, Inc., Edmonton, Alta, Canada.
  4. September 1993 – August 1997: Assistant Professor, Florida A&M University, College of Pharmacy, Tallahassee, FL, USA.
  5. September 1997-August 2002: Associate Professor, Florida A&M University, College of Pharmacy, Tallahassee, FL, USA.
  6. September 2002-to date: Professor, Florida A&M University, College of Pharmacy, Tallahassee, FL, USA.
  1. Novapharm Award for the year 1989-1990 for excellence in Biopharmaceutics.
  2. Outstanding scientist award in SynPhar Laboratories, 1992
  3. Teaching Incentive Professor award (TIP ) for 1999 at the College of Pharmacy, Florida A&M University.
  4. Adjunct faculty with the University of Miami, School of Medicine since 1998.
  5. Adjunct faculty with FAMU/FSU school of Biomedical Engineering since 2000.
  6. Section Leader for the Pharmaceutics Department.
  7. Teacher of the Year Award for 1999-2000. (Plaque and $2,000. This award is given across the whole campus).
  8. Superior Accomplishment Award, 2001. (Certificate and $500 cash Award)
  9. Researcher of the Year Award (2002) at Florida A&M College of Pharmacy (Plaque and Cash).
  10. Advanced Teacher of the Year Award (2003) at Florida A&M University (Plaque and Cash).
  11. Davis Productivity Award from the State of Florida in the Distinguished award category, 2004
  12. Superior Accomplishment Award, Florida A&M University, 2004.
  13. AACR HBCU faculty scholar award in 1999, 2000, and 2001. This award was given on a merit selection process and attended the American Association of Cancer Scientists meeting.
  14. Davis Productivity Award from the State of Florida, Certificate of Commendation (2006).
  15. William R. Jones Outstanding Mentor Award, 2006, from Florida Education fund.
  16. AAPS fellow award from AAPS for the year 2007.
  17. Who’s Who in America, 2008, 2009.
  18. Distinguished Alumnus Award from Panjab University, Chandigarh in 2008.
  19. Phi Lambda Sigma student fraternity award from FAMU for outstanding contribution in 2008.
  20. Research Excellence Award from FAMU for the year 2010. This included a cash award of $3000 and a plaque from the President of the University.
  21. Best Poster award, Nanotechnology symposium at University of Miami, 2010.
  22. Davis Productivity Award from the State of Florida, Plaque award (2011).
  23. Fulbright Scholar award at the Nanotechnology Institute, University of Sao Paulo (in Brazil, Science Beyond Borders) in 2013-2014.
  24. Davis Productivity award in the individual category from the State of Florida in 2015, Plaque and cash.
  25. Gian Fellow award for accomplished in Nanotechnology from Government of India for 2016.
  26. AAICR Cancer award for Cancer Scientist from American Association of Cancer Research fo 2017.
  1. Expertise in the formulation of Drug Delivery systems like:
    1. Liposomes, nanoparticles
    2. Polymeric microspheres
    3. Biomaterials for delivery of small molecule drugs and proteins/peptides and their evaluation in vitro and in vivo.
  2. Over 15 years of experience in cancer pharmacology, biology, and therapeutics with emphasis on:
    1. BreastCancer
    2. Lung Cancer
    3. Pancreatic Cancer
    4. Co-Cultures of different cancer cell lines to study Angiogenesis.
  3. Experience in skin irritation, permeation (of drugs and peptides), and skin toxicology.
  4. Other areas of expertise are:
    1. Inhalation and Nasal delivery systems with an emphasis on protein and peptide delivery.
    2. Development of in vitro 3D Culture models for Wound Healing and Anticancer Drug screening.
  1. American Association of Pharmaceutical Scientists (AAPS)
  2. American Association of Cancer Research (AACR)
  3. American Association of Colleges of Pharmacy (AACP)
  4. Controlled Release Society (CRS)
  5. Society of Toxicology (SOT)
  6. Society of Investigative Dermatology (SID)
  1. Bioconjugate Chemistry
  2. International Journal of Cancer
  3. Clinical Cancer Research 
  4. British Journal of Cancer
  5. Toxicology Letters
  6. Journal of Controlled Release
  7. Pharmaceutical Research 
  8. Journal of Pharmacy and Pharmacology 
  9. International Journal of Pharmaceutics
  10. Drug Development and Industrial Pharmacy
  11. International Journal of Pharmaceutical Compounding
Selected Publications
2004

1. Haynes A, Sudhan Madhu, Krarup H, and Mandip Singh. Evaluation of the Malvern Spraytec with inhalation cell to measure particle size distribution from metered-dose inhalers. J. Pharm. Sciences, 93:349-363, 2004. DOI: 10.1002/jps.10558. PMID: 14705192

2. Babu RJ, Kanikkannan N, Kikwai L, and Mandip Singh. Percutaneous Absorption and Anti-Inflammatory Effect of a Substance P Receptor Antagonist - Spantide II. Pharm. Res, 21:108-113, 2004. DOI: 10.1023/b:pham.0000012157.80716.73. PMID: 14984264

3. Babu RJ, Kanikkannan N, Kikwai L, and Mandip Singh. Preformulation stability of spantide II, a promising topical anti-inflammatory agent for treating psoriasis and contact dermatitis. J. Pharmacy and Pharmacology, 56:19-25, 2004. DOI: 10.1111/j.2042-7158.2004.tb02573.x. PMID: 14979997

4. Madhu Sudhan Shaik, Alfred Haynes, and Mandip Singh. Antiproliferative and antitumor effect of a cox-2 inhibitor, nimesulide. Clinical Cancer Research. 10: 1521-1529, 2004. DOI: 10.1158/1078-0432.ccr-0902-03. PMID: 14977856

5. Kanikkannan N, Andega S, Burton S and Mandip Singh. Formulation and in vitro evaluation of transdermal patches of melatonin. Drug development Industrial Pharmacy. 30: 1-8, 2004. DOI: 10.1081/ddc-120028716. PMID: 15089055

6. P Dayal, Shaik MS, and Mandip Singh. Evaluation of different parameters that affect droplet size distribution from nasal sprays using the Malvern Spraytec. Journal of Pharmaceutical Sciences 93, 1725:1742, 2004. DOI: 10.1002/jps.20090. PMID: 15176062

7. Madhu Sudhan Shaik, Chatterjee A, and Mandip Singh. Effects of monensin liposomes on the cytotoxicity, apoptosis, and expression of multidrug resistance genes in doxorubicin-resistant human breast tumor (MCF-7/dox) cell-line. J. Pharmacy and Pharmacology 56:899-907, 2004. DOI: 10.1211/0022357023772. PMID: 15233869

8. Babu RJ, Chatterjee A, and Mandip Singh. Assessment of skin irritation and molecular responses in rat skin exposed to nonane, dodecane, and tetradecane. Toxicology Letters 153:255-256, 2004. DOI: 10.1016/j.toxlet.2004.04.036. PMID: 15451557

9. R. J. Babu, A. Chatterjee, E. Ahaghotu, and Mandip Singh. Percutaneous absorption and skin irritation upon low level prolonged dermal exposures of nonane, dodecane, and tetradecane in hairless rats. Toxicology and Industrial Health, 20:109-118(2004). DOI: 10.1191/0748233704th197oa. PMID: 15941007

2005

10. Alfred Haynes, Madhu Sudhan Shaik, Chatterjee A and Mandip Singh Formulation and Evaluation of aerosolized celecoxib for treating Lung cancer. Pharmaceutical Research, 22(3):427-439, 2005. DOI: 10.1007/s11095-004-1881-z. PMID: 15835749

11. Chatterjee A, Babu RJ, and Mandip Singh. The effect of occlusive and unocclusive exposures of xylene and benzene on skin irritation and molecular responses in hairless rats. Arch Toxicology, 79:294-301(2005). DOI: 10.1007/s00204-004-0629-1. PMID: 15902427

12. E. Ahaghotu, R. J. Babu, Chatterjee, C and Mandip Singh. Effect of methyl substitution of benzene on the percutaneous absorption and skin irritation in hairless rats, Toxicol Lett. 159(3):261-71 (2005). DOI: 10.1016/j.toxlet.2005.05.020. PMID: 16087301

13. Dayal, P., Pillay, V. Babu, R. and Mandip Singh. The use of a Box–Behnken experimental design in the development of a nasal drug delivery system of hydroxyurea: characterization of viscosity, in vitro drug release, droplet size and dynamic surface tension. Awarded 2005 AAPS Outstanding Graduate Student Research Award in Pharmaceutical technologies- AAPS PharmSciTech. 2005 Nov 17:6(4):E573-85. DOI: 10.1208/pt060472. PMID: 16408859

14. Loice Kikwai, R. Jayachandra Babu, R. Oliveira, Cheryl A. Armstrong, John C. Ansel and Mandip Singh. In Vitro and In Vivo Evaluation of Topical Formulations of Spantide II. Awarded 2005 AAPS Outstanding Graduate Student Research Award in Pharmaceutical technologies- AAPS PharmSciTech. 2005 Oct 31:6(4):E565-72. DOI: 10.1208/pt060471. PMID: 16408858

2006

15. Madhu Sudhan Shaik, Abhijit Chatterjee, Tanise Jackson and Mandip Singh. Enhancement of Antitumor Activity of Docetaxel by Celecoxib in Lung Tumors. International Journal of Cancer. 118(2):396-404, 2006. DOI: 10.1208/pt060471. PMID: 16408858

16. Kikwai L, Babu RJ, Kanikkannan N, and Mandip Singh. Stability and Degradation Profiles of Spantide II in Aqueous Solutions. European Journal of Pharmaceutical Sciences 27:158-166, 2006. DOI: 10.1016/j.ejps.2005.09.005. PMID: 16266798

17. Anticancer effect of celecoxib and aerosolized docetaxel against human non-small cell lung cancer cell line, A549. Suniket V. Fulzele, Madhu Sudhan Shaik, Abhijit Chatterjee and Mandip Singh. J. Pharmacy and Pharmacology. 58:1-10, 2006. DOI: 10.1211/jpp.58.3.0006. PMID: 16536899

18. Suniket V. Fulzele, Abhijit Chatterjee, Madhu Sudhan Shaik, Tanise Jackson and Mandip Singh. Inhalation delivery and antitumor activity of Celecoxib in human orthotopic Non-small cell lung cancer xenograft model. Pharm. Res. 23(9):2094-106, 2006. DOI: 10.1007/s11095-006-9074-6. PMID: 16902813

19. Chatterjee, A., Babu RJ, M. Klausner and Mandip Singh. In vitro and in vivo comparison of dermal irritancy of jet fuel exposure using EpiDermTM (EPI-200) cultured human skin and hairless rats. Tox.Letters 1:167(2):85-94, 2006. DOI: 10.1016/j.toxlet.2006.08.017. PMID: 17049765

20. Zhu Donghui, Lennon SP, Peters MH, Finney WC and Mandip Singh. Brownian diffusion and surface kinetics of liposome and viral particle uptake by human lung cancer cells in vitro. Annals of Biomedical Engineering, 34(10)1573-1586, 2006. DOI: 10.1007/s10439-006-9158-9. PMID: 16933106

2007

21. R. Marijani, M.S.Shaik, A.Chatterjee and Mandip Singh. Development of metered dose inhaler formulation of cyclosporine. J. Pharmacy and Pharmacology, 59(1):15-21, 2007. DOI: 10.1211/jpp.59.1.0003. PMID: 17227616

22. Abhijit Chatterjee, Suniket V. Fulzele, Madhu Sudhan Shaik1, Tanise Jackson, Nkechi Ichite and Mandip Singh. 15-Deoxy-D12,14-Prostaglandin J2 (15d-PGJ2) enhancesdocetaxel antitumor activity by peroxisome proliferator-activated receptor (PPAR) dependent and independent pathways in human lung cancers. Anticancer Drugs: 18(1):65-78, 2007

23. Fulzele S, Ramapuram Jay, Mandip Singh. Estimation of proinflammatory biomarkers of skin irritation by dermal microdialysis following exposure with irritant chemicals.Toxicology. 237(1-3):77-88, 2007. DOI: 10.1016/j.tox.2007.05.005. PMID: 17574719

2008

24. Jackson Tanise, Chougule Mahavir, Nkechi, Ichite, Patlolla Ram and Mandip Singh. Antitumor activity of Noscapine in Human Non-small cell lung cancer xenograft model. Cancer Chemother Pharmacol. 2008, 63(1):117-26. DOI: 10.1007/s00280-008-0720-z. PMID: 18338172

25. Dayal P, Babu J, Mandip Singh. Effect of Cyclodextrins on the complexation and nasal permeation of melatonin. Drug Delivery. 2008, 15(6):381-8. DOI: 10.1080/10717540802006922. PMID: 18686082

2009

26. Nkechi Ichite, Suniket V. Fulzele, Abhijit Chatterjee , Selina F. Darling-Reed, Stephen Safe and Mandip Singh. Enhancement of Docetaxel Anticancer Activity by A Novel Diindolylmethane (DIM) Compound in H460 Non-Small Cell Lung Cancer (NSCLC) Cells. Clinical Cancer Research. 2009; 15(2):543-52. DOI: 10.1158/1078-0432.CCR-08-1558. PMID: 19147759

27. Ram Patlolla , Jay Ramapuram, Mandip Singh. Dermal Microdialysis of Inflammatory Markers Induced by Aliphatic Hydrocarbons in Rats. Toxicology Letters. 2009, 185(3):168-74. DOI: 10.1016/j.toxlet.2008.12.012. PMID: 19152832

28. Patel G, Chougule M, Mandip Singh, Misra A, Nanoliposomal dry powder formulations, Methods in Enzymology, 2009;464:167-91. DOI: 10.1016/S0076-6879(09)64009-X. PMID: 19903555

2010

29. Mallampati R, Patlolla RR, Agarwal S, Babu RJ, Hayden P, Klausner M, Mandip SinghS. Evaluation of EpiDerm full thickness-300 (EFT-300) as an in vitro model for skin irritation: Studies on aliphatic hydrocarbons. Toxicol In Vitro. 2010, 24(2):669-76. DOI: 10.1016/j.tiv.2009.08.019. PMID: 19720135

30. Kandimalla, K, Jayachandra Babu Ramapuram, and Mandip Singh. Biphasic Flux Profiles: The Yin-Yang of Transdermal Permeation Enhancement Mediated by Fatty Alcohol Enhancers. J Pharm Sci. 2010, 99(1):209-18. DOI: 10.1002/jps.21812. PMID: 19530074

31. Patlolla R, Chougule M and Mandip Singh. Formulation, Characterization and Pulmonary Deposition of Nebulized Celecoxib Encapsulated Nanostructured Lipid Carriers. J. Control Release, 2010, 144(2):233-41. DOI: 10.1016/j.jconrel.2010.02.006. PMID: 20153385

32. Patlolla R, Desai P, Belay K and Mandip Singh. Translocation of cell penetrating peptide engrafted nanoparticles across skin layers. Biomaterials, 2010; 31(21):5598-607. DOI: 10.1016/j.biomaterials.2010.03.010. PMID: 20413152

33. Desai P, Patlolla R and Mandip Singh. Interaction of Nanoparticles and Cell Penetrating Peptides with Skin (Review). "Invited Review for Thematic issue on Nanoparticles: Crossing Barriers and Membrane Interactions, 2010, 27(7):247-59. DOI: 10.3109/09687688.2010.522203. PMID: 21028936

34. Ichite N, Chougule M, Patel A and Mandip Singh. Inhalation Delivery of a Novel Diindolylmethane Derivative for the Treatment of Lung Cancer. Molecular Cancer Therapeutics, 2010, 9(11):3003-14. DOI: 10.1158/1535-7163.MCT-09-1104. PMID: 20978159

35. Chougule M, Patel AR, Sachdeva P, Jackson T, Mandip Singh. Anticancer activity of Noscapine, an opioid alkaloid in combination with Cisplatin in human non-small cell lung cancer. Lung Cancer. 2010, 71(3):271-82. DOI: 10.1016/j.lungcan.2010.06.002. PMID: 20674069

2011

36. M Chougule, A R. Patel, T Jackson, Mandip SinghAntitumor activity of Noscapine in combination with Doxorubicin in triple negative breast cancer. PLOS One. 2011; 6(3):e17733. DOI: 10.1371/journal.pone.0017733. PMID: 21423660

37. Jayachandra Babu R, Dayal PP, Pawar K, Mandip Singh. Nose-to-brain transport of melatonin from polymer gel suspensions: a microdialysis study in rats. J Drug Target. 2011, 19(9):731-40. DOI: 10.3109/1061186X.2011.558090. PMID: 21428693

38. Chougule M, Patel A, Sachdeva P and Mandip Singh. Enhanced anticancer activity of gemcitabine in combination with noscapine via antiangiogenic and apoptotic pathway against non-small cell lung cancer. Plos One, 2011;6(11), e27394. DOI: 10.1371/journal.pone.0027394. PMID: 22102891

2012

39. Shah PP, Desai P, Patel A, Mandip Singh. Skin permeating nanogel for cutaneous inflammation using combination approach. Biomaterials. 2012. 33(5):1607-17. DOI: 10.1016/j.biomaterials.2011.11.011. PMID: 22118820

40. Shah PP, Desai P, Mandip Singh. Effect of oleic acid modified polymeric bilayered nanoparticles on percutaneous delivery of spantide II and ketoprofen. J Control Release. 2012. 158 (2):336-345. DOI: 10.1016/j.jconrel.2011.11.016. PMID: 22134117

41. A.R. Patel, S. D. Spencer, M. B. Chougule, Mandip Singh. A combined zero order/michaelis- menten limited absorption; three compartment disposition model describes the oral pharmacokinetic behavior of a highly lipophilic methylene-substituted 3, 3'-diindolylmethane (DIM) in vitamin-E TPGS. Eur J Pharm Sci. 2012, May 12;46(1-2)8-16. DOI: 10.1016/j.ejps.2012.01.012. PMID: 22342559

42. Shah PP*, Desai PR*, Channer D, Mandip Singh. Enhanced skin permeation using polyarginine modified nanostructured lipid carriers. J Control Release. 2012 Aug 10;161(3):735-45. DOI: 10.1016/j.jconrel.2012.05.011. PMID: 22617521

43. Desai P, Shah PP, Patlolla R, Mandip Singh. Dermal microdialysis technique to evaluate the trafficking of surface modified lipid nanoparticles upon topical application. Pharm Res. 2012 Sep 29 (9):2587-600. DOI: 10.1007/s11095-012-0789-2 . PMID: 22644591

44. Lee SO, Andey T, Jin UH, Kim K, Mandip Singh, Safe S. The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53. Oncogene. 2012 Jul 5;31(27):3310. DOI: 10.1038/onc.2011.504. PMID: 22081070

2013

45. Desai P, Shah PP, Hayden P, Mandip Singh. Investigation of follicular and non-follicular pathways for polyarginine and oleic acid modified nanoparticles. Pharm Res, 2013 May;30(5). DOI: 10.1007/s11095-012-0939-6. PMID: 23187866

46. Patel AR, Chougule MB, Patlolla R, Gwandi W, Ian T, Jackson T, Mandip Singh. Anticancer activity in combination of docetaxel and celecoxib nanostructured lipid carriers, Pharm Res. 2013 May;30(5):1435-46. doi: 10.1007/s11095-013-0984-9. PMID: 23361589

47. C Godugu*, A Patel*, U Desai, M Chougule, A Sams, Mandip Singh. In vitro algimatrix™ 3D cell culture system, an alternative to mammalian models for non-small cell lung cancer. PLoS One. 2013;8(1):e53708. (* Contributed equally). DOI: 10.1371/journal.pone.0053708. PMID: 23349734

48. Andey T, Patel A, Jackson T, Safe S, Mandip Singh.1,1-Bis (3'-indolyl)-1-(p-substituted phenyl)methane compounds inhibit lung cancer cell and tumor growth in a metastasis model. Eur J Pharm Sci. 2013 Oct 9;50(2):227-41. DOI: 10.1016/j.ejps.2013.07.007. PMID: 23892137

49. Desai P, Marepally S, Mandip Singh. Topical delivery of anti-TNFalpha siRNA and capsaicin via novel lipid-polymer hybrid nanoparticles efficiently inhibits skin inflammation in vivo. Journal of Controlled Release, 2013 Aug 28;170(1):51-63. DOI: 10.1016/j.jconrel.2013.04.021. PMID: 23643662

50. Cedar H. A. Boakye, Ravi Doddapaneni, Punit P. Shah, Apurva R. Patel, Chandraiah Godugu, Stephen Safe, Santosh K. Katiyar, Mandip Singh. Chemoprevention of skin cancer with 1,1-bis (3’-indolyl)-1-(aromatic) methane analog through induction of the orphan nuclear receptor, NR4A2 (Nurr1). PLoS One 2013 Aug 7;8(8):e69519. DOI: 10.1371/journal.pone.0069519. PMID: 23950896

51. Godugu C, Patel AR, Doddapaneni R, Marepally S, Jackson T, Mandip Singh. Inhalation delivery of Telmisartan enhances intratumoral distribution of nanoparticles in lung cancer models. J Control Release. 2013 Nov 28;172(1):86-95. DOI: 10.1016/j.jconrel.2013.06.036. PMID: 23838154

2014

52. Desai P, Shah PP, Parvastu A, Mandip Singh. 31P Solid-state NMR based monitoring of permeation of cell-penetrating peptides into skin. European J of Pharmaceutical Sciences 2014 Feb;86(2):190-9. DOI: 10.1016/j.ejpb.2013.05.003. PMID: 23702274

53. Punit Shah, Pinaki Desai, Ram Patlolla, Mandip Singh Effect of a combination of hydrophilic and lipophilic permeation enhancers on the skin permeation of Kahalalide F. Accepted in J. Pharmacy and Pharmacology, 2014 Jun;66(6):760-8. DOI: 10.1111/jphp.12206. PMID: 24697673

54. Patel AR, Chougule MB, Lim E, Francis KP, Safe S, Mandip Singh. Theranostic tumor homing nanocarriers for the treatment of lung cancer. Nanomedicine. 2014 Jul;10(5):1053-63. DOI: 10.1016/j.nano.2013.12.002. PMID: 24355163

55. Mahavir Chougule, Apurva Patel, Ram Patlolla, Mandip Singh. Epithelial transport of Noscapine across cell monolayers and influence of absorption enhancers on in vitro permeation and bioavailability: Implications for intestinal absorption. J. Drug Targeting,2014 Jul;22(6):498-508. DOI: 10.3109/1061186X.2014.894046. PMID: 24731057

56. Apurva Patel and Mandip Singh. EphA2 targeting pegylated nanocarrier drug delivery system for treatment of Lung Cancer. Pharm Res. 2014 Oct;31(10):2796-809. DOI: 10.1007/s11095-014-1377-4. PMID: 24867421

57. Terrick Andey, Srujan Marepally, Apurva Patel, Tanise Jackson, Shubhashish Sarkar, Malaney O’Connell, Pomila Mandip Singh, Cationic lipid guided short-hairpin RNA interference of Annexin A2 attenuates tumor growth and metastasis in a mouse lung cancer stem cell model. J Control Release. 2014 Jun 28;184:67-78. DOI: 10.1016/j.jconrel.2014.03.049. PMID: 24727000

58. Jamal S, Cheriyan VT, Muthu M, Munie S, Levi E, Ashour AE, Pass HI, Wali A, Mandip Singh, Rishi AK. CARP-1 functional mimetics are a novel class of small molecule inhibitors of malignant pleural mesothelioma cells. PLos One. 2014 Mar 5;9(3). DOI: 10.1371/journal.pone.0089146. PMID: 24598827

59. Apurva Patel, Kevin Francis and Mandip Singh. Opening Up the Optical Imaging Window Using Nano-Luciferin. Pharm Res. 2014 Nov; 31(11):3073-84. DOI: 10.1007/s11095-014-1400-9. PMID: 24831312

60. Chandu Godugu, Apurva Patel and Mandip Singh. Approaches to improve the oral bioavailability and effects of novel anticancer drugs berberine and betulinic acid. PLoS One. 2014 Mar 10;9(3):e89919. doi: 10.1371/journal.pone.0089919. PMID: 24614362

61. Marepally S, Boakye CH, Patel AR, Godugu C, Doddapaneni R, Desai PR, Mandip Singh. Topical administration of dual siRNAs using fusogenic lipid nanoparticles for treating psoriatic-like plaques. Nanomedicine (Lond). 2014 Jul; 9 (14) 2157-74. DOI: 10.2217/nnm.13.202. PMID: 24593003

62. Somagoni J, Boakye CH, Godugu C, Patel AR, Mendonca Faria HA, Zucolotto V, Mandip Singh. Nanomiemgel-a novel drug delivery system for topical application-in vitro and in vivo evaluation. PLoS One. 2014 Dec 29;9(12). DOI: 10.1371/journal.pone.0115952. PMID: 25546392

2015

63. Cedar H. A. Boakye, Punit P. Shah, Ravi Doddapaneni, Apurva R. Patel, Stephen Safe, and Mandip Singh. Enhanced Percutaneous Delivery 1,1-bis(3-indolyl)-1-(p-chlorophenyl) Methane for skin cancer chemoprevention. J. Biomed. Nanotechnol. 2015; 11:1269-1281. DOI: 10.1166/jbn.2015.2064. PMID: 26307849

64. Magesh Muthu, Abdelkader E. Ashour, Jagan Mohan Somagoni, Kaladhar B. Reddy, Alaa Eldeen B Yassin, Scott D. Larsen, Vino T. Cheriyan, Ahmed M. Alafeefy, Mandip Singh and Arun K. Rishi. Identification and testing of novel CARP-1 functional mimetic compounds as inhibitors of non-small cell lung and triple negative breast cancers. Journal of Biomedical Nanotechnology. 2015 Sep; 11 (9):1608-1627. DOI: 10.1166/jbn.2015.2099. PMID: 26485930

65. Cedar Boakye, Ketan Patel and Mandip Singh. Doxorubicin liposomes as an investigative model to study the skin permeation of nanocarriers. Int J Pharm. 2015 Jul 15;489(1-2):106-16. DOI: 10.1016/j.ijpharm.2015.04.059. PMID: 25910414

66. Patel AR, Godugu C, Wilson H, Safe S, Mandip Singh. Evaluation of Spray BIO-Max DIM-P in Dogs for Oral Bioavailability and in Nu/nu Mice Bearing Orthotopic/Metastatic Lung Tumor Models for Anticancer Activity. Pharm Res. 2015 Jul; 32(7):2292-300. DOI: 10.1007/s11095-015-1620-7. PMID: 25576245

67. Andey T, Sudhakar G, Marepally S, Patel A, Banerjee R, Mandip Singh. Lipid Nanocarriers of a Lipid-Conjugated Estrogenic Derivative Inhibit Tumor Growth and Enhance Cisplatin Activity against Triple-Negative Breast Cancer: Pharmacokinetic and Efficacy Evaluation. Molecular Pharmaceutics. 2015 Apr 6;12(4):1105-20. DOI: 10.1021/mp5008629. PMID: 25661724

68. Patel AR, Doddapaneni R, Andey T, Wilson H, Safe S, Mandip Singh Evaluation of self-emulsified DIM-14 in dogs for oral bioavailability and in Nu/nu mice bearing stem cell lung tumor models for anticancer activity. J Control Release. 2015 Jun 14; 213:18-26. DOI: 10.1016/j.jconrel.2015.06.014. PMID: 26079185

69. Hedrik E, Lee So, Doddapaneni R, Mandip Singh Safe s. Nuclear receptor 4A1 (NR4A1) as a drug target for breast cancer chemotherapy. Endor Relat Cancer. 2015 Oct:22(5):831-40. DOI: 10.1530/ERC-15-0063. PMID: 26229035

70. Ketan Patel, Nusrat Chowdhury, Doddapaneni R, Cedar Boakye, Mandip Singh Piperlongumine for enhancing oral bioavailability and cytotoxicity of Docetaxel in Triple -negative Breast Cancer. J. Pharm. Sciences.2015 Dec; 104(12): 417-26. DOI: 10.1002/jps.24637. PMID: 26372815

2016

71. Boakye CH, Patel K, Doddapaneni R, Bagde A, Chowdhury N, Safe S, Mandip Singh Ultra-flexible nanocarriers for enhanced topical delivery of a highly lipophilic antioxidative molecule for skin cancer chemo prevention. Colloids Surf B Biointerfaces 2016 Jul 1;143:156-67. DOI: 10.1016/j.colsurfb.2016.03.036. PMID: 27003466

72. Patel K, Doddapaneni R, Boakye CH, Godugu C, Mandip Singh, Tumor stromal disrupting agent enhances the anticancer efficacy of docetaxel loaded PEGylated liposomes in lung cancer. Nanomedicine (Lond), 2016 Jun;11(11):1377-92. DOI: 10.2217/nnm.16.37. PMID: 27171485

73. Hedrick E, Lee SO, Doddapaneni R, Mandip Singh, Safe S. NR4A1 Antagonists inhibit B1- Integrin-dependent Breast Cancer cell migration. Mol Cell Biol. 2016 May 1; 36(9): 1383–1394. DOI: 10.1128/MCB.00197-17. PMID: 28847971

74. Doddapaneni R, Patel K, Chowdhury N, Mandip Singh, Noscapine chemosensitication enhances docetaxel anticancer activity and nanocarrier uptake in triple negative breast cancer. Exp Cell Res. 2016 Aug 1;346(1):65-73. DOI: 10.1016/j.yexcr.2016.05.006. PMID: 27177833

75. Patel K, Doddapaneni R, Sekar V, Chowdhury N, Mandip Singh, Combination approch of YSA peptide anchhored Docetaxel Stealth liposomes with oral antifibrotic agent for the treatment of Lung cancer. Mol Pharm. 2016 Apr 12;13(6):2049-58. DOI: 10.1021/acs.molpharmaceut.6b00187. PMID: 27070720

76. Lacey A, Hedrick E, Li X, Patel K, Doddapaneni R, Mandip Singh, Safe S. Nuclear receptar 4A1 (NR4A1) as a drug targer for treating rhabdomyosarcoma (RMS).Oncotarget. 2016 May 24;7(21):31257-69. DOI: 10.18632/oncotarget.9112. PMID: 27144436

77. Vino T. Cheriyan, Magesh Muthu, Ketan Patel, Sreeja Sek har, Lisa Polin, Mandip Singh, Arun Rishi, CARP-1 functional mimetics are novel inhibitor of drug-resistant triple-negative breast cancers. Oncotarget, 2016 Nov 8; 7(45): 73370–88. DOI: 10.18632/oncotarget.12333. PMID: 27687593

78. Godugu C, Doddapaneni R, Mandip Singh, Safe S, Novel Diindolylmethane derivatives based NLC formulations to improve the oral Bioavailability and anticancer effects in Triple Negative Breast Cancer.European Journal of Pharmaceutics and Biopharmaceutics. 2016 Nov;108:168-179. DOI: 10.1016/j.ejpb.2016.08.006. PMID: 27586082

79. Udofot O, Affram K, Smith T, Tshabe B, Krishnan S, Mandip Singh, Agyare E, Pharmacokinetic, biodistribution and therapeutic efficacy of 5-fluorouracil-loaded pH-sensitive PEGylated liposomal nanoparticles in HCT-116 tumor-bearing mouse. Journal of Nature and Science, 2016;2(1). pii: e171. PMID: 27200415

80. Safe S Jin UH, Morpurgo B, Abudayyeh A, Mandip Singh. Tjalkens RB. Nuclear receptor 4A (NR4A) family - orphans no more. J Steroid Biochem Mol Biol.2016 Mar;157:48-60. DOI: 10.1016/j.jsbmb.2015.04.016. PMID: 25917081

81. Godugu, Doddapaneni R, Patel AR, Singh R, Mercer R, Mandip Singh. Novel Gefitinib Formulation with improved Oral Bioavailability in Treatment of A431 Skin Carcinoma. Pharm Res. 2016 Jan; 33(1): 137-154. DOI: 10.1007/s11095-015-1771-6. PMID: 26286185

2017

82. Boakye CH, Patel K, Doddapaneni R, Bagde A, Marepally S, Mandip Singh. Novel amphiphilic lipid augments the co-delivery of erlotinib and IL36 siRNA into a skin for psoriasis treatment. J Control Release. 2017 Jan 28;246:120-132. DOI: 10.1016/j.jconrel.2016.05.017. PMID: 27170227

83. Chandraiah Godugu, Ravi Doddapaneni, Mandip Singh, Honokiol nanomicellar formulation produced increased oral bioavailability and anticancer effects in triple negative breast cancer (TNBC), Colloids and Surfaces B: Bio interfaces, 2017 May 1;153: 208-219. DOI: 10.1016/j.colsurfb.2017.01.038. PMID: 28249200

84. Nusrat Chowdhury, Imran Vohra, Ketan Patel, Ravi Doddapaneni, Arindam Mondal, Mandip Singh, Liposomes Co-loaded With 6-Phosphofructo-2-Kinase/Fructose-2, 6-Biphosphatase 3 (PFKFB3) shRNA Plasmid And Docetaxel For The Treatment Of Non-Small Cell Lung Cancer, Pharm Res (2017). Pharm Res. 2017 Nov; 34(11): 2371-2384. DOI: 10.1007/s11095-017-2244-x. PMID: 28875330

85. Shallu Kutlehria, Gautam Behl, Ketan Patel, Ravi Doddapaneni, Nusrat Chowdhury, Arvind Bagde, Imran Vhora, Mandip Singh, Cholecalciferol-PEG conjugate based nanomicelles of doxorubicin for treatment of triple negative breast cancer, AAPS PharmaSciTech, (2017);19(83). https://doi.org/10.1208/s12249-017-0885-z. PMID: 29019073

86. Kevin Affram, Ofonime Udofot, Mandip Singh, Sunil Krishnan, Rosenberg, Rene Reams and Edward Agyre, Smart thermosensitive liposomes for effective solid tumor therapy and in vivo imaging, PLoS One. 2017 Sep; 12(9): e0185116. DOI: 10.1371/journal.pone.0185116. PMID: 28934281

87. Ravi Doddapaneni, Ketan Patel, Nusrat Chowdhury & Mandip Singh, Reversal of drug-resistance by noscapine chemo-sensitization in docetaxel resistant triple negative breast cancer, Scientific Reports 7, Article number: 15824(2017) doi:10.1038/s41598-017-15531-1. PMID: 29158480

2018

88. Arvind Bagde, Arindam Mondal, Mandip Singh. Drug delivery strategies for chemoprevention of UV-B induced skin cancer: a Review, Photodermatology, photoimmunology and photomedicine, 2018 Jan; 34: 60–68. DOI: 10.1111/phpp.12368. PMID: 29150967

89. Shallu Kutlehria, Imran Vhora, Arvind Bagde, Nusrat Chowdhury, Gautam Behl, Ketan Patel, Mandip Singh. Tacrolimus loaded PEG-Cholecalciferol based Nanomicelles for Treatment of Ocular Inflammation. Pharmaceutical Res. 2018 Apr 16;35(6):117. PMID: 29663141

90. Nusrat Chowdhury, Imran Vhora, Ketan Patel, Arvind Bagde, Shallu Kutlehria and Mandip Singh. Development of hot melt extruded solid dispersion of tamoxifen citrate and resveratrol for synergistic effects on breast cancer cells, AAPS PharmSciTech (2018). https://doi.org/10.1208/s12249-018-1111-3. PMID: 30218267

91. Cheriyan, V. T., Alsaab, H., Sekhar, S., Venkatesh, J., Mondal, A., Vhora, I., Mandip Singh, Rishi, A. K. (2018). A CARP-1 functional mimetic compound is synergistic with BRAF-targeting in non-small cell lung cancers. Oncotarget, 9(51), 29680-29697. http://doi.org/10.18632/oncotarget.25671. PMID: 30038713

2019

93. Arvind Bagde, Ketan Patel, Arindam Mondal, Shallu Kutlehria, Nusrat Chowdhury, Aragaw Gebeyehu, Nilkumar Patel, Nagi Kumar, Mandip Singh,Combination of UVB absorbing Titanium dioxide and Quercetin Nanogel for skin cancer chemoprevention, AAPS PharmSciTech, June 2019, 20: 240. https://doi.org/10.1208/s12249-019-1424-x. PMID: 31250221

94. Arvind Bagde, Ketan Patel, Shallu Kutlehria, Nusrat Chowdhury, Mandip Singh, Formulation of topical Ibuprofen solid lipid nanoparticle (SLN) gel using hot melt extrusion technique (HME) and determining its anti-inflammatory strength, Drug Delivery and Translational Research. March 2019, https://doi.org/10.1007/s13346-019-00632-3. PMID: 30924025

95. Terrick Andey, PhDa, NamrataBora-Singhal, Srikumar Chellappan, Mandip Singh, Cationic lipoplexes for treatment of cancer stem cell-derived murine2lung tumors. Nanomedicine: Nanotechnology, Biology and Medicine. March 2019. doi: 10.1016/j.nano.2019.02.007. PMID: 30831275

96. Ketan Patel, Ravi Doddapaneni, Manali Patki, Vasantkumar Sekar, Arvind Bagde, Mandip Singh, Erlotinib-valproic acid liquisolid formulation: Evaluating oral bioavailability and cytotoxicity in erlotinib resistant non-small cell lung cancer cells. AAPS PharmSciTech. April 2019, 20:135. DOI: 10.1208/s12249-019-1332-0. PMID: 30830506

97. Kutlehria S, Bagde A, Patel N, Mandip Singh. Whole-Eye Perfusion Model for Screening of the Ocular Formulations via Confocal Laser Scanning Microscopy. AAPS PharmSciTech. 2019 Oct 1;20(7):307. DOI: 10.1208/s12249-019-1493-x. PMID: 31515645

98. Peddakkulappagari, CS, Saifi, MA, Khurana, A, Anchi, P, Mandip Singh, Godugu, C. Withaferin A ameliorates renal injury due to its potent effect on inflammatory signaling. BioFactors. 2019; 1– 13. https://doi.org/10.1002/biof.1534. PMID: 31188510

99. Sayed,N, Khurana, A, Saifi, MA, Mandip Singh, Godugu, C. Withaferin A reverses bile duct ligation‐induced liver fibrosis by modulating extracellular matrix deposition: Role of LOXL2/Snail1, vimentin, and NFκB signaling. BioFactors. 2019; 1– 16. https://doi.org/10.1002/biof.1546. PMID: 31336025

100. Mondal A, Gebeyehu A, Miranda M, Bahadur D, Patel N, Ramakrishnan S, Rishi AK, Mandip Singh. characterization and printability of Sodium alginate-Gelatin hydrogel for bioprinting nScLc co-culture. Scientific Reports. 2019 Dec 27;9(1):1-2. DOI: 10.1038/s41598-019-55034-9. PMID: 31882581

101. Green, R., Howell, M., Khalil, Mandip Singh, R.et al. Actinomycin D and Telmisartan Combination Targets Lung Cancer Stem Cells Through the Wnt/Beta Catenin Pathway. Sci Rep 9, 18177 (2019). https://doi.org/10.1038/s41598-019-54266-z. PMID: 31796785

102. Miranda MA, Mondal A, Sachdeva M, Cabral H, Neto YA, Khan I, Groppo M, McChesney JD, Bastos JK. Chemosensitizing effect of cernumidine extracted from solanum cernuum on bladder cancer cells in vitro. Chemistry & biodiversity. 2019 Oct;16(10):e1900334. PMID: 31448497

2020

103. Ebony Nottingham, Arindam Mondal, Vasantkumar Sekar, A Rishi, Steven Safe, Mandip Singh, The role of Self Nano Emulsifying drug delivery systems of CDODA-Me in sensitizing Erlotinib resistant Nonsmall cell lung cancer. Journal of Pharmaceutical Sciences. 2020 Jan 15. pii: S0022-3549(20)30015-0 https://doi.org/10.1016/j.xphs.2020.01.010. PMID: 31954111

104. Ebony Nottingham, Elizabeth Mazzio, Shallu Kutlehria, Ramesh Badisa, Mandip Singh “Whole transcriptomic analysis to delineate major synergistic effects of methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate (CDODA-Me) and Erlotinib in (ERL) in ERL resistant lung cancer HCC827 cells” Lung Cancer (Under Review)

105. Shallu Kutlehria, Thanh Cong Dinh, Arvind Bagde, Nilkumar Patel, Aragaw Gebeyehu, Mandip Singh, High‐throughput 3D bioprinting of corneal stromal equivalents, Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2020/5/9, https://doi.org/10.1002/jbm.b.34628. PMID: 32386281

106. Dingani Nkosi, Li Sun, Leanne C. Duke, Nilkumar Patel, Sunil K. Surapaneni, Mandip Singh, David G. Meckes Jr. Epstein-Barr Virus LMP1 Promotes Syntenin-1- and Hrs-Induced Extracellular Vesicle Formation for Its Own Secretion to Increase Cell Proliferation and Migration. mBio Jun 2020, 11 (3) e00589-20; DOI: 10.1128/mBio.00589-20

107. Parker Arnett1, Avra Kundu, Arvind Bagde, Nilab Azim, Mandip Sachdeva and Swaminathan Rajaraman1.DLP 3d printed “intelligent” microneedle array (iµna) for stimuli responsive release of drugs and its in vitro and ex vivo characterization. 1 University of Central Florida, Orlando, FL, USA; 2 Florida A&M University, Tallahassee, FL, USA, IEEE Journal of Microelectromechanical Systems (accepted for publication)

108. Peggy Arthur, Nilkumar Patel, Sunil Surapaneni, Arindam Mondal, Arvind Bagde, Shallu Kutlehria, Ebony Nottingham, Aragaw Gebeyehu, Mandip Singh. Targeting Lung Cancer stem cells using combination of Telmisartan and Docetaxel Liposomes in 3D cultures and tumor xenografts. Toxicology and Applied Pharmacology. Available online 12 June 2020, 115112: https://doi.org/10.1016/j.taap.2020.115112

109. Miranda MA, Marcato PD, Mondal A, Chowdhury N, Gebeyehu A, Surapaneni SK, Bentley MVLB, Amaral R, Pan CX, Singh M Cytotoxic and chemosensitizing effects of glycoalkaloidic extract on 2D and 3D models using RT4 and patient derived xenografts bladder cancer cells.Mater Sci Eng C Mater Biol Appl. 2021 Feb;119:111460. doi: 10.1016/j.msec.2020.111460. Epub 2020 Aug 27.

110. Claudia M. Trujillo-Vargas, Shallu Kutlehria, Humberto Hernandez, Rodrigo G. de Souza, Andrea Lee, Zhiyuan Yu, Stephen C. Pflugfelder,2 Mandip Singh, and Cintia S. de Paiva. Rapamycin Eyedrops Increased CD4+Foxp3+ Cells and Prevented Goblet Cell Loss in the Aged Ocular Surface. Int J Mol Sci. 2020 Dec; 21(23): 8890.

111. Shyam Mohaptra, Robert Frisnia, Subhra Mohapatra, Mandip Singh. Advances in Translational Nanotechnology: Challenges and Opportunities. Appl. Sci. 2020, 10, 4881; doi:10.3390/app10144881

112. Bagde A, Patel N, Patel K, Nottingham E, Singh M. Sustained release dosage form of noscapine HCl using hot melt extrusion (HME) technique: formulation and pharmacokinetics. Drug Deliv Transl Res. 2020 Sep 3. doi: 10.1007/s13346-020-00838-w. Online ahead of print.

2021

113. Kommineni N, Nottingham E, Bagde A, Patel N, Rishi A, R S Dev S, Singh Mandip. Role of Nano-lipid Formulation of CARP-1 mimetic, CFM-4.17 to Improve Systemic Exposure and Response in Osimertinib Resistant Non-Small Cell Lung Cancer. Eur J Pharm Biopharm. 2021 Jan; 158: 172-184. doi: 10.1016/j.ejpb.2020.11.007.

  1. US patent titled ‘Modified nanostructured lipid carrier nanoparticles formulations for dermal drug delivery’ in April 2009. US Patent # 8,715,736.
  2. US patent application, “Surface Modified Multi-Layered Nanostructures for Dermal Delivery” in 2011. The patent has now been granted, US Patent # 8,647,661 B1.
  3. Filed a US patent entitled “Dual-channel spray-dried modified multi-layered microstructures for oral delivery” in 2011.
  4. Filed a US patent entitled “Dual-channel Ultrasonic gun spray-dried modified multi-layered microstructures for oral delivery” in 2011.
  5. Filed a US patent, Novel Nanoparticle systems for Medical and preclinical imaging. Filed in 2013.
  6. US patent titled ‘Alpha-Melanocyte-stimulating hormone (α-MSH) as a topical anti-inflammatory agent for treating allergic contact dermatitis and eczema. The patent now has been granted, US Patent #8,846,616.
  7. Surface Modified Multilayered Nanostructures for Dermal Delivery’ US Patent #8,865,206.
  8. Methods and formulation for topical treatment of Psoriasis. US Patent #9,867,827.
  9. Method of Preparing Modified Multilayered Microstructures with Enhanced Oral Bioavailability. US Patent #9,968,557.
  10. Self-emulsifying formulation of CARP-1 functional mimetics US Patent: 10220025. 2019
  1. Ghose T, Singh M, Faulkner G. Goundalkar A, Mezei M. Antibody Aided Liposomal Drug Delivery. In: Liposomes as drug carriers, edited by Gregoriadis G. pp 697-708 (1988).
  2. Mandip Singh. Targeting with Transferrin. Chapter in a book titled Tumor targeting in Cancer Therapy. Eds Michel Page, Humana Press. Pp 151-164, 2002.
  3. Narayanasamy Kanikkannan, Jayachandra Babu Ramapuram and Mandip Singh. Structural-activity relationship of chemical penetration enhancers. Book chapter in Percutaneous Penetration Enhancers vol. 2, Edited by Eric Smith and Howard Maibach pp17-34, 2005.
  4. Jayachandra Babu Ramapuram, Narayanasamy Kanikkannan and Mandip Singh. Fatty alcohols and Fatty acids. Book chapter in Percutaneous Penetration Enhancers vol. 2, Edited by Eric Smith and Howard Maibachpp137-158, 2005.
  5. Singh and R. J. Babu, Chromatography, Remington: The Science and Practice of Pharmacy, 21st Edition, Lippincott William and Wilkins, Chapter 33, 599-625.
  6. RJ Babu, R. Patlolla, and Singh. Methods of assessing skin irritation and sensitization of Jet Fuels. In: Jet Fuel Toxicology Edited by Mark L. Witten, Errol Zeiger, and Glenn D. Ritchie CRC Press 2011 Pages 135–148.
  7. Srujan Marepally and Mandip Singh. Nucleic Acid-Based Therapy in Dermatology. Accepted as a chapter inNanotheranostics of Nanobiomedicine, Vol 6. Edited by Mandip Singh Sachdeva and Anton Liopo. Stadium Publishers, 2014.
  8. Apurva Patel, Kevin Francis, Mandip Singh. Emerging Newer Nanotechnology Techniques for Imaging Cancer. Nanotheranostics of Nanobiomedicine, Vol 6., Stadium Publishers, 2014.
  9. Chandu Godugu and Mandip Singh.AlgiMatrix™ Based 3D Cell Culture System as an In Vitro Model: an important tool in cancer research. Chapter in a Book titled, Cancer Chemoprevention: Methods and Protocols, edited by Sabrina Stano, Springer publications, 2015.

Books Edited:

  1. Nanotheranostics, Edited by Drs Mandip Sachdeva and Anton Lipo, Stadium Publishers, 2014.
  1. Abhijit Chatterjee, Mandip Singh. Combination therapy with resveratrol and a cyclooxygenase-2 (COX-2) inhibitor nimesulide in A549, a nonsmall cell lung tumor. Presented at the AAPS meeting in Baltimore in Nov 2004.
  2. Madhu Sudhan Shaik, Abhijit Chatterjee, Tanise Jackson, and Mandip Singh. Celecoxib Enhances the Antitumor Activity of Docetaxel in A549 Nonsmall cell Lung Tumor. Presented at the AAPS meeting in Baltimore in Nov 2004.
  3. Rukia Marijani, Abhijit Chatterjee, Mandip Singh. Evaluation Of metered-dose inhaler (MDI) of cyclosporine and inhibition of IL-2 production. Presented at the AAPS meeting in Baltimore in Nov 2004.
  4. P. P. Dayal, V. Pillay, R. J. Babu, M. Singh, The Use Of A Box-behnken Experimental Design In The Development Of A Nasal Drug Delivery System Of Hydroxyurea: Characterization Of Viscosity, Droplet Size, And Drug Release. Presented at the AAPS meeting 2004, Baltimore, Maryland
  5. R. J. Babu, N. Kanikkannan, L. Kikwai, A. Kundra, M. Singh, Skin Permeation Enhancement, Barrier Changes And Irritation Of Sulfhydryl Compounds Using Melatonin As A Model Compound. Presented in the AAPS meeting 2004, Baltimore, Maryland
  6. R. J. Babu, N. Kanikkannan, L. Kikwai, M. Singh, Development Of Topical Gels Of A Novel Anti-inflammatory Peptide - Spantide-II. Presented at the AAPS meeting 2004, Baltimore, Maryland
  7. E. Ahaghotu, R. J. Babu, M. Singh. Skin Permeation, Retention, And Irritation Responses Of Benzene, Xylene, And Naphthalene In Hairless Rats. Presented in the AAPS meeting 2004, Baltimore, Maryland.
  8. Abhijit Chatterjee, R. Babu, Mandip Singh. Evaluation of a tissue-engineered human skin epiderm 3-D culture as a model to study irritation after jet fuel exposure. Presented at the SOT meeting on Mar 6-10, 2005.
  9. J. Ramapuram, E. Ahagotu and M. Singh. Effect of methyl substitution of benzene on the percutaneous absorption and skin irritation in hairless rats. Presented at the SOT meeting on Mar 6-10, 2005, 84.
  10. Abhijit Chatterjee, Suniket Fulzele, Madhu Sudhan Shaik Tanise Jackson, Mandip Singh. A cyclooxygenase (COX)-2 inhibitor and PPAR-gamma agonist enhance the antitumor effect of docetaxel in lung tumors in mice. AACR Annual Meeting, Anaheim, CA, April 16-20, 2005.
  11. Mandip Singh, Madhu Sudhan Shaik, and Abhijit Chatterjee. Antiproliferative effect of the combined treatment of celecoxib with docetaxel liposomes in human lung adenocarcinoma cell line. AACR Annual Meeting, Anaheim, CA, April 16-20,2005.
  12. S.V.Fulzele, R. J. Babu, E. Ahaghotu, M.Singh. Dermal microdialysis of proinflammatory neurochemicals as markers of skin irritation after exposure with JP-8 chemicals. SOT Annual Meeting, San Diego, CA. March 2006.
  13. R.J.Babu, Abhijit Chatterjee, S.V.Fulzele, S.Verma, M.Singh. Effect of prolonged low-level exposures of JP-8 on the biomarker expressions in the skin of Wistar rats. SOT Annual Meeting, San Diego, CA. March 2006.
  14. M.Singh, R.J.Babu, Abhijit Chatterjee, S.V.Fulzele, S.; Klausner, M.; Kubilus. Evaluation of epiderm as a model to study irritation after exposure to various aliphatic hydrocarbons found in jet fuels, SOT Annual Meeting, San Diego, CA. March 2006.
  15. M.Singh, S.V.Fulzele, R.J.Babu, R.Prado, C.Armstrong and J.Ansel. Percutaneous absorption and anti-inflammatory effect of alpha-MSH. Presented at AAPS annual meeting, San Antonio, Oct-Nov 2006.
  16. M.Singh, S.V.Fulzele, R.J.Babu, R.Prado, C.Armstrong, and J.Ansel. Evaluation of in vitro dermal kinetics of substance P receptor antagonist, SR 140333. AAPS annual meeting, San Antonio, Oct-Nov 2006.
  17. S.V.Fulzele, R.J.Babu, E.Ahaghotu and M.Singh. Dermal microdialysis for quantitative measurement of local neuropeptides as markers of skin irritation in rats. Presented at AAPS annual meeting, San Antonio, Oct-Nov 2006.
  18. S.V.Fulzele, M.S.Shaik, A.Chatterjee, T.Jackson, and M.Singh. Inhalation delivery and anti-tumor activity of celecoxib in human orthotopic non-small cell lung cancer xenograft model. Presented at AAPS annual meeting, San Antonio, Oct-Nov 2006.
  19. S V Fulzele, R. J. Babu, E. Ahaghotu and M. Singh. Investigation of Dermal irritation potential of selected jet fuel chemicals (nonane, dodecane, and tetradecane) by in vivo microdialysis. Presented at the Annual Meeting of Society of Toxicology, Charlotte, NC, March 25-29, 2007.
  20. N Ichite, S Fulzele, R Aneja, S F. Darling-Reed, S Safe, and M Singh. Enhancement of docetaxel anticancer activity by a novel DIM compound in H460 nonsmall cell cancer cell lines. Presented at the American Association of Cancer Research Meeting at Los Angeles in April 2007.
  21. M. Singh, R. Mallampati, P. Hayden, M. Klausner, RR. Patlolla, RJ. Babu. Evaluation Of Epiderm Full Thickness-300 (Eft-300) As An In Vitro Model For Skin Irritation. Poster presented at Society of Toxicology Meeting, Seattle, April 2008.
  22. Mahavir B. Chougule, Ram R. Patlolla, Tanise Jackson, Apurva R. Patel, and Mandip Singh. Nebulization of Celecoxib Loaded Nanostructured Lipid Carriers: Preparation, Characterization, Pharmacokinetics and Lung Deposition. Poster Presented at RDD 2008.
  23. Nkechi Ichite, Mahavir Chougule, Tanise Jackson, Stephen Safe, and Mandip Singh. Characterization of Aerosolized Diindolylmethane (DIM) Derivative as a Potential Inhalation Delivery Agent Against Lung Cancer. Poster Presented at American Association of Cancer Research Meeting, San Diego, April 2008.
  24. Apurva Patel, Mahavir Chougule, Ram Patlolla, Nkechi Ichite, and Mandip Singh, Anti-Tumor Effect Of Noscapine In Combination With Antitumor Agents Against Non-Small Cell Lung Cancer, Poster Presented at GRASP, Florida A & M University, Tallahassee, June 2008.
  25. P. Vashi, R. Mallampati, R.R. Patlolla, M.B. Chougule, R.J. Babu and M. Singh, In-vitro permeation of Alpha MSH formulations in Human and Ratskin, Poster Presented at GRASP, Florida A & M University, Tallahassee, June 2008 (Second Price Winner).
  26. R. Mallampati, R. R. Patlolla, P.vashi, P. Hayden, M. Klausner, and M. Singh, Study Of Wound Healing With In-Vitro Epiderm Full Thickness (EFT-300) Model, Poster Presented at GRASP, Florida A & M University, Tallahassee, June 2008.
  27. P. Vashi, R.R. Patlolla, J. Samaan, M.B. Chougule, and M. Singh. In-vitro skin permeation of anti-inflammatory peptide encapsulated Nanolipid Crystal (NLC) nanoparticles. Poster Presented at NanoFlorida conference, University of Central Florida, September 2008, Orlando, FL.
  28. R. Patel, R. R. Patlolla, M.B. Chougule, K. Kandimalla, T. Jackson, and Mandip Singh. Aerosol characterization and lung deposition of celecoxib encapsulated lipid Nanoparticles—poster Presented at NanoFlorida conference, University of Central Florida, September 2008, Orlando, FL.
  29. R. Patel, M.B. Chougule, R. R. Patlolla, T. Jackson, and Mandip Singh, Novel nanocrystal-based gastro retentive gel formulation to enhance oral bioavailability, Poster presented at MBRS-2008, FAMU, Tallahassee, Awarded best poster award.
  30. Samaan J, Patlolla RR, Mallampati. R, Vashi P, Chougule MB, Singh MS. Topical Delivery of Ibuprofen Encapsulated Cell-Penetrating Peptide Engrafted Lipid Nanoparticles. Graduate Feeder Conference and Student Research Forum at FAMU, Tallahassee FL, October 2008.
  31. P. Vashi, R.R. Patlolla, M.B. Chougule, R.Mallampati, J. Samman, R.J. Babu, and M. Singh. In-vitro skin permeation of Spantide II encapsulated Nanolipid Crystal (NLC) nanoparticles using Franz Diffusion cells. Graduate Feeder Conference and Student Research Forum at FAMU, Tallahassee FL, October 2008.
  32. R.R.Patlolla, M.B. Chougule, K. Kandimalla, T. Jackson, A. R. Patel, and Mandip Singh. Pulmonary Deposition and Pharmacokinetics of Nebulized Celecoxib Loaded Nanostructured Lipid Carriers. Poster Presented at AAPS annual meeting, November 2008, Atlanta, GA.
  33. R.R. Patlolla, M.B. Chougule, P. Vashi, J. Samman, R.J. Babu, and M. Singh. Encapsulation and in-vitro skin permeation of Spantide II encapsulated Nanolipid crystal (NLC) nanoparticles. Poster Presented at AAPS annual meeting, November 2008, Atlanta, GA.
  34. Mahavir Chougule, Ram Patlolla, Edward Agyare, Karunya Kandimala, and Mandip Singh, pH-Dependent Bidirectional Transport of Noscapine across Caco-2 and MDCK Monolayers: Implications for intestinal absorption, Poster Presented at AAPS annual meeting, November 2008, Atlanta, GA.
  35. Nkechi Ichite, Mahavir Chougule, Tanise Jackson, Stephen Safe, and Mandip Singh. Inhalation Drug Delivery of a Novel Diindolyl Methane Derivative for the Treatment of Lung Cancer, Poster Presented at AAPS annual meeting, November 2008, Atlanta, GA.
  36. R. Marijani, M. Chougule and M. Singh, Evaluation of Aggregation and Spray Characteristics of Nasal Formulations of Human Growth Hormone. Poster Presented at AAPS annual meeting, November 2008, Atlanta, GA.
  37. R. Mallampati, R.R. Patlolla, J. Andrew, Y. Lu, S.V. Fulzele, R.J. Babu, C. Armstrong, J. Ansel, and M. Singh. Anti-inflammatory activity of Alpha MSH lotion formulations in ACD model. Poster Presented at AAPS annual meeting, November 2008, Atlanta, GA.
  38. Ramya Mallampati, R.R.Patlolla, R.J. Babu, M.Klausner, P.Hayden, M.Singh.To study dermal irritancy of aliphatic hydrocarbons (C9-C16) using the invitro Epidermal Full Thickness (EFT-300) Model. Poster presented at Society of Toxicology meeting, March 2009, Baltimore, MD.
  39. M.Singh, Ramya Mallampati, R.R. Patlolla, P.Vashi, P.Hayden, M.Klausner.To develop an in-vitro ( EFT-300 ) skin model for the study of wound healing. Poster presented at Society of Toxicology meeting, March 2009, Baltimore, MD.
  40. Mahavir Chougule, Ram Patlolla, Apurva Patel and Mandip Singh, Transepithelial Transport of Noscapine and influence of permeation enhancers across Caco-2 and MDCK Monolayers, Submitted for poster presentation at AAPS annual meeting, Los Angeles, California November 2009.
  41. Mahavir Chougule, Apurva Patel, Ram Patlolla and Mandip Singh, Antitumor activity of Noscapine, an oral chemotherapeutic agent in human breast cancer xenograft model, Submitted for poster presentation at AAPS annual meeting, Los Angeles, California November 2009.
  42. R. Patel, M.B. Chougule, R. R. Patlolla, T. Jackson, and Mandip Singh., Physiological & pharmacokinetic evaluation of novel 3,3'Diindolylmethane derivative (DIM-C-pPhC6H5), Presented at GRASP, Mercer University, Atlanta, 2009.
  43. U.Desai, R.Patlolla, P. Vashi, M. Chougule, and M. Singh. A Novel Modified Liposome As A Potential Carrier For Gene Delivery, GRASP, Mercer University, Atlanta GA, June 2009.
  44. M. Wright, R.R. Patlolla, P. Desai, M.Chougule and M. Singh, Topical Delivery and Characterization of Novel Lipid Nanoparticles, Graduate Feeder Conference and Student Research Forum at FAMU, Tallahassee FL, October 2009 (First Price Winner).
  45. P. Desai, R.R. Patlolla, M.Chougule, and M. Singh, Translocation and In-vitro Permeation of Cell-Penetrating Peptide Engrafted Nano-Structured Lipid Carrier Nanoparticles across the Skin Layers, Graduate Feeder Conference and Student Research Forum at FAMU, Tallahassee FL, October 2009 (Second Price Winner).
  46. U. Desai, RR. Patlolla, R.Mallampati, P. Hayden, M. Klausner, M. Singh. Evaluation of Epiderm Full Thickness (EFT-300) as an In Vitro Model for Wound Healing. Graduate Feeder Conference and Student Research Forum at FAMU, Tallahassee FL, October 2009 (Second Price Winner).
  47. R. Patel, M.B. Chougule, R. R. Patlolla, T. Jackson, S. Safe, and Mandip Singh. Pharmacokinetic Evaluation of 3,3'Diindolylmethane derivative (DIM-C-pPhC6H5): A Novel Anticarcinogenic Compound. Graduate Feeder Conference and Student Research Forum at FAMU, Tallahassee FL, October 2009
  48. Terrick, M.B. Chougule, and Mandip Singh., Anticancer activity of NUR77 agonist against nonsmall cell lung cancer, Presented at GRASP, Mercer University, Atlanta, 2009.
  49. R. Patel, M.B. Chougule, R. R. Patlolla, T. Jackson, and Mandip Singh., Novel C-substituted Diindolylmethane derivative: Transepithelial permeability across caco-2 monolayer and pharmacokinetic evaluation. Presented at AAPS annual meeting, Los Angeles, California November 2009. AAPS Travelship Award.
  50. T.A. Terrick, M.B. Chougule, S. Safe, and Mandip Singh., Induction of apoptosis by nur-active 1, 1-bis(3’-indolyl)-1-(p-substituted phenyl)methanes in non-small cell lung cancer cells. Presented at Annual Research Forum, Florida A&M University, Tallahassee, 2009. (First Price Winner)
  51. P. Vashi, R.R. Patlolla, J. Samaan, M.Chougule and M. Singh. Topical Delivery and Characterization of Celecoxib Encapsulated Cell-Penetrating Peptide Engrafted Nanolipid Crystal Nanoparticles. Presented at GRASP, Mercer University, Atlanta, 2009.
  52. Patlolla, R.R., Patel, A., Chougule, M.B. and Singh, M. In vitro dissolution vs. in vitro cytotoxicity of celecoxib encapsulated nanostructured lipid carrier nanoparticles in NSCLC cell lines. Presented at AAPS annual meeting, Los Angeles, California November 2009.
  53. Patlolla, R.R., Vashi, P., Samaan, J., Chougule, M.B., Babu, R.J. and Singh, M. Translocation of Cell-Penetrating Peptide Engrafted Nanoparticles across the Skin Layers. Presented at AAPS annual meeting, Los Angeles, California November 2009.
  54. Patlolla, R.R., Utkarsh, D., Vashi, P., Chougule, M.B. and Singh, M. Encapsulation of plasmid DNA in liposomes using modified ethanol destabilization method and enhancing the transfection with cell-penetrating peptide. Presented at AAPS annual meeting, Los Angeles, California November 2009.
  55. P. Vashi, R.R. Patlolla, J. Samaan, M.Chougule and M. Singh. Topical Delivery of Celecoxib Encapsulated Cell-Penetrating Peptide Engrafted Nanostructured Lipid Carrier Nanoparticles. Presented at AAPS annual meeting, Los Angeles, California November 2009.
  56. Patel, A.R., Jackson, T., Safe, S., and Sachdeva, M.S. Inhalation delivery and evaluation of antitumor and antiangiogenic activity of novel 1, 1-bis(3’indolyl)-1-(p-biphenyl) methane analog in combination with docetaxel in mice. Third Annual Joint Student Research Forum and FAMU Graduate Feeder Conference, Florida A&M University, September 30, 2010, Tallahassee, FL. Received 1st place in Biological Sciences.
  57. Desai, P.R., Patolla, R.R., Shah, P.P., and Singh, M. In vivo permeation of cell-penetrating peptide modified lipid Nanoparticles formulations in rat skin. Third Annual Joint Student Research Forum and FAMU Graduate Feeder Conference, Florida A&M University, September 30, 2010, Tallahassee, FL. Received 3rd place in Nanoscience
  58. Andey, T.A., Chougule, M.B., Jackson, T., Safe, S., and Sachdeva, M.S. 1,1-Bis(3-indolyl)-1-(p-substituted phenyl)methane compounds inhibit tumor growth and metastasis in mouse models of A549 lung cancer, as activators and inhibitors of the orphan nuclear receptor, TR3. Third Annual Joint Student Research Forum and FAMU Graduate Feeder Conference, Florida A&M University, September 30, 2010, Tallahassee, FL. Received 3rd place in Biological Sciences.
  59. Channer, D., Desai, P., Shah, P., Patolla, R., and Singh, M. Topical delivery of anti-inflammatory drugs by using novel lipid Nanoparticles in vitro and in vivo. Third Annual Joint Student Research Forum and FAMU Graduate Feeder Conference, Florida A&M University, September 30, 2010, Tallahassee, FL.
  60. Apurva, R Patel, Mahavir B Chougule, Ram Patlolla, Shawn D Spencer, and Mandip Singh. Pharmacokinetic modeling and In Vitro-In Vivo Correlation (IVIVC) of methylene-substituted 3, 3’ diindolylmethane (DIM). AAPS meeting in New Orlean, 2010. Pharmacokinetics, Pharmacodynamics and Drug Metabolism (PPDM) Section Travelship Award
  61. Apurva, R Patel, Mahavir B Chougule, Ram Patlolla, Shawn D Spencer, and Mandip Singh. Physiologically based pharmacokinetic modeling of novel analog of 3, 3'-diindolylmethane (DIM): Intravenous and Inhalational exposure in mice. AAPS meeting in New Orlean, 2010.
  62. Chougule, M, Patel, A., and Singh, M. Multifunctional nanocarriers of synergistically acting Noscapine and Doxorubicin conjugated with CREKA peptide for the treatment of estrogen receptor-negative breast cancers. AAPS meeting in New Orleans, 2010. AAPS Travelship Award.
  63. Chougule, M, Patlolla, R.R., Patel, A., and Singh, M. Anticancer Efficacy of Celecoxib encapsulated nanostructured lipid carrier in treating non-small cell lung cancer. AAPS meeting in New Orlean, 2010
  64. Desai, P. R., R. R. Patlolla, P. P. Shah, K. Belay, M. Sachdeva. Translocation and Quantification of Surface Modified Lipid Nanocarriers Across Rat Skin Using Confocal Microscopy and Microdialysis. AAPS meeting in New Orleans, 2010.
  65. T. A. Andey, M. B. Chougule, R. Patlolla, T Jackson, S. Safe, M. S. Sachdeva. C-substituted Diindolylmethane (C-DIM) Analogs Induce Apoptosis in Non-Small Lung Cancer (NSCLC) Cells as Agonists and Antagonists of the Orphan Nuclear Receptor, NUR77/TR3 In Vivo. AAPS meeting in New Orleans, 2010. American Association of Indian Pharmaceutical Scientists (AAiPS) Award.
  66. Punit P. Shah, P. R. Desai, R.R. Patlolla, K. Belay, and M. Singh. In Vivo Studies of Cell-Penetrating Peptide Coated Lipid Nanocarriers for Skin-Targeted Drug Delivery. 2010 Biomedical Nanoscience Initiative of University of Miami ("BioNIUM") Retreat, 9th and 10th December 2010. 2nd prize winner
  67. P. R. Desai, R.R. Patlolla, P. P. Shah, S. Hira, G. Strouse, K. Belay, and M. Singh. In Vivo Evaluation of Cell-Penetrating Peptide Modified Nanocarriers On The Release of Pro-Inflammatory Biomarkers In The Rat Skin. The Inaugural Fowler Symposium Frontiers in Molecular Biology, 17th December 2010.
  68. T. A. Andey, M. B. Chougule, Syng Oak-Lee, T Jackson, S. Safe, M. S. Sachdeva. 1,1-Bis(3-Indolyl)-1-(p-Substituted Phenyl) Methane Compounds Inhibit Tumor Growth and Metastasis in Mouse Models of A549 Lung Cancer, as Activators and Inhibitors of the Orphan Nuclear Receptor, TR3. The Inaugural Fowler Symposium Frontiers in Molecular Biology, 17th December 2010.
  69. M Singh, P.P. Shah, U.S. Desai, R.R. Patlolla, M.Klausner, P. Hayden. Use of Epiderm Full Thickness (EFT) Skin Cultures as an in vitro model for wound healing. SOT 50th Annual Meeting, 6th–10th March 2011.
  70. Mandip Singh, Apurva Patel, Mahavir Chougule, and Alexander Sams. In Vitro AlgiMatrix™ 3D Cell Culture System, An Alternative to Mammalian Models For Non-Small Cell Lung Cancer. Presented at the Society of Toxicology meeting in 2011 in Washington DC.
  71. P. R. Desai, A. Cormier, P. P. Shah, R.R. Patlolla, A. K. Paravastu and M. Singh. Tracking and quantification of surface-modified nanocarriers across skin layers. GRASP, Massachusetts College of Pharmacy and Health Sciences, Boston. June 2011.
  72. Terrick Andey, Apurva Patel, Tanise Jackson, Stephen Safe, Mandip Singh, Pulmonary Delivery and Anticancer Activity of Novel Diindolylmethane Analogs in an A549-induced Metastatic Tumor Model. GRASP, Massachusetts College of Pharmacy and Health Sciences, Boston. June 2011 (Second Price Winner).
  73. P. R. Desai, P. P. Shah, A. Cormier, R.R. Patlolla, A. K. Paravastu and M. Singh. Surface Modified Lipid Nanocarriers: Evaluation of Spantide II and Ketoprofen Loaded Novel Nanocarriers for Topical Delivery. Gordon Research Conference, Waterville Valley, NH. August 7-12, 2011.
  74. P. R. Desai, P. P. Shah, D. Channer, and M. Singh. Topical delivery of oleic acid surface-modified bilayered polymeric nanoparticles. GRASP, Massachusetts College of Pharmacy and Health Sciences, Boston. June 2011.
  75. P. R. Desai, P. P. Shah and M. Singh. Skin Permeating Nanogel (Nonoease) for Cutaneous Inflammation Using Combination Approach. Presenting at 2011 NOBCChE Health Science and BioTechnology Midwest Regional Conference. Indianapolis IN, November 2011. Travel Fellowship Award by Eli Lilly and Company
  76. Patel, A., Andey, T. and Singh, M. Evaluation of In Vitro AlgiMatrix™ 3D Cell Culture System as an Alternative to Mammalian Models For Non-small Cell Lung Cancer. AAPS Annual Meeting & Exposition, Washington DC, October 2011.
  77. Patel, A., Jackson, T., Safe, S., and Sachdeva, M.S. Novel Dual channel Spray-dried enteric-coated Self-emulsifying Drug delivery system for Enhanced Oral absorption of anti-cancer agents. AAPS Annual Meeting & Exposition, Washington DC, October 2011.
  78. P. Desai, P. Shah, M. Singh. Investigation of penetration pathways of topically applied surface-modified nanoparticles. AAPS Annual Meeting & Exposition, Washington DC, October 2011.
  79. P. Desai, A. Cormier, P. Shah, R. Patlolla, A. Paravastu, M. Singh. Tracking of cell-penetrating peptide modified lipid nanoparticles in the skin using solid-state NMR and confocal laser microscopic techniques. AAPS Annual Meeting & Exposition, Washington DC, October 2011.
  80. P. Desai, P. Shah, D. Channer, M. Singh. Effect of oleic acid surface modification of bilayered polymeric nanoparticles on topical delivery. AAPS Annual Meeting & Exposition, Washington DC, October 2011.
  81. P. Shah, P. Desai, R. Patlolla, M. Singh. In Vivo Efficacy of Cell-Penetrating Peptide Modified Nanocarriers to Treat Topical Inflammation. AAPS Annual Meeting & Exposition, Washington DC, October 2011.
  82. P. Shah, P. Desai, D. Channer, M. Singh. Transport of spantide II and ketoprofen across the skin by surface-modified nanostructured lipid carriers. AAPS Annual Meeting & Exposition, Washington DC, October 2011.
  83. P. Shah, P. Desai, D. Channer, K. Belay, M. Singh. Effect of oleic acid modified poly-(lactide-glycolic acid)-chitosan nanoparticles on skin permeation of ibuprofen. AAPS Annual Meeting & Exposition, Washington DC, October 2011.
  84. P. Shah, P. Desai, D. Channer, M. Singh. Nanogel system for enhanced percutaneous delivery of spantide II and ketoprofen. AAPS Annual Meeting & Exposition, Washington DC, October 2011.
  85. Terrick Andey, Apurva Patel, Tanise Jackson, Stephen Safe, Mandip Singh. Pulmonary Delivery and Anticancer Activity of Novel Diindolylmethane Analogs in an A549-induced Pulmonary Metastatic Tumor Model. AAPS Annual Meeting & Exposition, Washington DC, October 2011.
  86. Terrick Andey, Apurva Patel, Tanise Jackson, Stephen Safe, Mandip Singh. Permeability Profiling of Novel C-substituted Diindolylmethane (C-DIM) Compounds. AAPS Annual Meeting & Exposition, Washington DC, October 2011.
  87. Terrick Andey, Apurva Patel, Tanise Jackson, Stephen Safe, Mandip Singh, Pulmonary Delivery and Anticancer Activity of Novel Diindolylmethane Analogs in an A549-induced Metastatic Tumor Model. GRASP, Massachusetts College of Pharmacy and Health Sciences, Boston. June 2011 (2nd Prize Winner).
  88. Apurva Patel, Ed Lim, Ning Zhang, Kevin Francis, Stephen Safe, Mandip Singh. In-vivo imaging of lung cancer using tumor homing peptide coated nanoparticles. AACR Annual Meeting 2012 in Chicago, Illinois.
  89. Mandip Singh, Terrick Andey, Sandeep Singh, Apurva Patel, Chandraiah Godugu, Stephen Safe, Srikumar Chellappan. Sensitization of Chemoresistant H1650 Lung Cancer Stem Cells to Chemotherapy by Combination Treatment with Novel Diindolylmethane Compounds. AACR Annual Meeting 2012 in Chicago, Illinois.
  90. Singh M, Shah PP, Armento A, Hayden P. Develop protocols for investigating the burn wound healing process in epidermal fulfill epidermal thickness (EFT-400) in vitro skin cultures. SOT Annual Meeting 2012.
  91. Activation of Nurr1 by a Novel Diindolylmethane Derivative Encapsulated Nanoparticles for Chemoprevention of UVB Induced Skin Cancer, Punit Shah, Cedar Boakye, Apurva Patel, Mandip Singh, Florida A&M University. AAPS annual meeting 2012.
  92. C-substituted Diindolylmethane Compounds Regulate Stemness and Inhibit Growth of H1650 Lung Cancer Stem Cells T. Andey, S. Singh, A. Patel, C. Godugu, S. Chellappan, S. Safe, M. Singh, Florida A&M University, H. Lee Moffitt Cancer Center, 3 Texas A&M Health Science Center. AACR annual meeting 2012.
  93. Effect of Combination of Hydrophilic and Lipophilic Permeation Enhancers on the Skin Permeation of Kahalalide F. P. P. Shah, P. R. Desai, R. Patlolla, L. Klevans, M. Singh Florida A&M University, Dr. Reddy's Laboratories, Medimetriks Pharmaceuticals, Inc. AAPS 2012.
  94. Novel Diindolylmethane Derivatives Inhibits Triple-Negative Breast Cancer (TNBC) and ErbB2-Positive Breast Cancer (EPBC). C. Godugu, A. S. Prather, N. Zharmouh, S. Safe, M. Singh Florida A&M University, Texas A&M Health Science Center. AAPS 2012.
  95. Enhanced Skin Permeation of α-melanocyte Stimulating Hormone for the Treatment of Inflammatory Skin Disorders M. Singh, P. P. Shah, P. R. Desai, C. Boakye, R. Mallampati, S. V. Fulzele, R. J. Babu, 1 Florida A&M University, Cima Labs, Auburn University. AAPS 2012.
  96. Novel Diindolylmethane Derivatives Prevent Initiation and Progression of Skin Cancer through Endoplasmic Reticulum Stress-induced Apoptosis. C. H. Boakye, P. Shah, A. R. Patel, S. Safe M. Singh. Florida A&M University, Texas A&M University. AAPS 2012.
  97. Novel Dual feed Spray Dried Bio-adhesive Controlled Release Drug Delivery System for Enhanced Oral Absorption of Anti-cancer Agents. A. R. Patel, C. Godugu, S. Safe, M. Singh Florida A&M University, Texas A & M Health Science Center. AAPS 2012.
  98. Oral Delivery of C-substituted Diindolylmethane Inhibits Tumor Growth in an Orthotopic Murine Cancer Model. T. Andey, A. Patel, T. Jackson, S. Safe, M. Singh. Florida A&M University, Texas A&M Health Science Center. AAPS 2012.
  99. Spray Dried Controlled Released System for Enhanced Oral Absorption of Gefitinib. A. R. Patel, C. Godugu, T. Jackson, M. Singh. Florida A&M University. AAPS 2012.
  100. Theranostic Tumor Homing Pegylated Nanocarrier Drug Delivery System for Treatment of Cancer. A. R. Patel, E. Lim, N. Zhang, K. Francis, S. Safe, M. Singh. Florida A&M University, Caliper Life Sciences, Texas A&M Health Science Center. AAPS 2012.
  101. Topical Delivery of Anti-TNFα siRNA and Capsaicin via Novel Keratolytic Lipid-polymer Hybrid Nanoparticles can Efficiently Inhibit Skin Inflammation In Vivo. P. R. Desai, S. Marepally, A. R. Patel, M. Singh. Florida A&M University. AAPS 2012
  102. The Influence of Cyclic Head Group of Cationic Amhiphile in Transdermal Delivery S. K. Marepally, P. Desai, M.Singh, A. Chaudhuri. Florida A&M University, Indian Institute of Chemical Technology. AAPS 2012.
  103. Chandraiah Godugu, Apurva Patel, Ravi Doddapaneni, Jagan Somagoni, Mandip Sachdeva. Spray Dried Micro Beads Increases the Oral Bioavailability and Anticancer Effects of Berberine in Lung Cancer Models. AAPS, San Antonio, TX, 2013.
  104. Chandraiah Godugu, Apurva Patel, Srujan Marepally, Ravi Doddapaneni, Jagan Somagoni, Mandip Sachdeva. Telmisartan Produces Better Intratumoral Nanoparticles Distribution and Anticancer Effects Compared to Losartan. AAPS, San Antonio, TX, 2013.
  105. Jagan Somagoni, Chandraiah Godugu, Apurva Patel, Mandip Sachdeva. Development and validation of bioanalytical HPLC method for Honokiol in rat plasma: Application to pharmacokinetic studies. AAPS, San Antonio, TX, 2013.
  106. Jagan Somagoni, Chandraiah Godugu, Apurva Patel, Mandip Sachdeva. Development of Nanocarriers by Quality by Design and Pharmacokinetic analysis of anti-cancer agent. AAPS, San Antonio, TX, 2013.
  107. Terrick Andey, Srujan Marepally, Pomila Singh, Mandip Singh. 2013. Single-nucleotide liposomal formulation of AnnexinA2 shRNA using a novel cationic lipid induces apoptosis and inhibits angiogenesis in lung cancer stem cells. AAPS Annual Meeting & Exposition, San Antonio, TX, 2013.
  108. Terrick Andey, Srujan Marepally, Mandip Singh. Absorption and physicochemical characterization of a self-emulsifying lipid-modified estrogen derivative in a self-nano emulsifying drug delivery (SNEDD) system. AAPS Annual Meeting & Exposition, San Antonio, TX, 2013.
  109. Terrick Andey, Srujan Marepally, Pomila Singh, Mandip Singh. 2013. Liposomal Annexin A2 small Hairpin RNA-mediated inhibition of angiogenesis in lung cancer stem cells. Cancer Nanotechnology, Gordon Research Conference. Mount Snow, VT, 2013.
  110. Apurva Patel, Ed Lim, Kevin Francis, Mandip Singh. Breaking Limits of Pre-clinical Optical Imaging Using Nano-Luciferin. AAPS, San Antonio, TX, 2013.
  111. Apurva Patel, Jagan Somagoni, Mandip Singh. EphA2 Targeting Pegylated Nanocarrier Drug Delivery System for Treatment of Non-small Cell Lung Cancer. AAPS, San Antonio, TX, 2013.
  112. Ravi Doddapaneni. Cedar H. A. Boakye, Punit P. Shah, Apurva R. Patel, Stephen Safe, Mandip Singh. Nurr 1 a novel target of 1,1-bis(3’-indolyl)-1-(p-chlorophenyl) methane to inhibit the initiation and progression of skin cancer tumorigenesis. American Association of Cancer Research (AACR) 2014, San Diego, CA.
  113. Jaganmohan Somagoni, Chandraiah Godugu, Ravi Doddapaneni, Ketan Patel, Arun K Rishi and Mandip Singh. Nano Lipid Carrier system of a Novel Cell Cycle and Apoptosis Regulatory Protein (CARP-1) Mimetic agent to Combat Non-Small Cell Lung Cancer-In Vitro and In vivo. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2014, San Diego, CA.
  114. Jaganmohan Somagoni, Ketan Patel, Ravi Doddapaneni, Nusrat Chowdhury1 Arun K Rishi and Mandip Singh. Novel Cell Cycle and Apoptosis Regulatory Protein (CARP-1) Mimetic Agent Loaded Nano Lipid Formulation to Combat Triple-Negative Breast Cancer. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2014, San Diego, CA.
  115. Jaganmohan Somagoni, Ketan Patel, Madhavi Gangapuram, Kinfe Ken Redda, Mandip Singh. Preparation of nano lipid carriers of novel 4-ethyl-N-(1,2,3,4-tetrahydroisoquinoline-2-yl)benzamide/Sulfobutylether-β-cyclodextrin complex: its more potent effect on MDA-MB-231& MIA PaCa-2 Cells. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2014, San Diego, CA.
  116. Jaganmohan Somagoni, Cedar H.A. Boakye, Chandraiah Godugu, Apurva R. Patel, Henrique Antonio Mendonca Faria, Valtencir Zucolotto and Mandip Singh. Nanomiemgel-A novel drug delivery system for overcoming the skin barrier function: in vitro and in vivo evaluation. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2014, San Diego, CA.
  117. Jaganmohan Somagoni, Chandraiah Godugu, Ravi Doddapaneni, Stephen H Safe, and Mandip Singh. Treatment of pulmonary arterial hypertension by using a novel PPAR gamma agonist, diindolylmethane, in a nanoparticle formulation. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2014, San Diego, CA.
  118. Ketan Patel, Jaganmohan Somagoni, Ravi Doddapaneni, Nusrat Chowdhury, and Mandip Singh. Evaluation of cytotoxic interaction of docetaxel and cancer-selective ROS mimetic natural compound – Piperlongumine. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2014, San Diego, CA.
  119. Ketan Patel, Jaganmohan Somagoni, Ravi Doddapaneni, Nusrat Chowdhury, and Mandip Singh. Docetaxel PEGylated liposomes with tumor stromal disrupting agent for lung cancer treatment. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2014, San Diego, CA.
  120. Cedar H. A. Boakye, Ketan Patel, Jagan M. Somagoni, Apurva R. Patel, Mandip Singh. Oral lipid-based drug delivery tablet of a lipophilic diindolylmethane derivative for skin cancer chemoprevention. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2014, San Diego, CA.
  121. Cedar H. A. Boakye, Srujan Marepally, Apurva R. Patel, Chandraiah Godugu, Ravi Doddapaneni, Pinaki Desai, Mandip Singh. Simultaneous percutaneous delivery of dual siRNA by novel pyrrolidium lipid inhibits Psoriasis’s IL23/TH17 signaling pathway. Abstract for Podium Presentation. 33rd Graduate Research Association of Students in Pharmacy (GRASP) Conference, March 4th-5th, 2014. St John’s University, Queens, NY.
  122. Nusrat Chowdhury, Jagan Somagoni, Ravi Doddapaneni, Chandraiah Godugu, Mandip Singh. Docetaxel and Piperlongumine loaded Nanostructured lipid carrier: Synergistic combination with superior antitumor efficacy against triple-negative breast cancer. 33rd Graduate Research Association of Students in Pharmacy (GRASP) Conference, March 4th-5th, 2014. St John’s University, Queens, NY. Awarded best poster award
  123. Ravi Doddapaneni, Ketan Patel, Mandip Singh. The synergistic anticancer effect of Noscapine and Camptothecin is mediated through apoptosis and cell cycle arrest in A549 lung cancer. American Association of Cancer Research (AACR) Annual Meeting, April 18th-22nd, 2015, Philadelphia, PA.
  124. Arvind Bagde, Ketan Patel, Cedar Boakye, Mandip Singh. Development of Lipid-Based Topical Formulation of Anti-inflammatory Drugs using HME Technology. 34th Graduate Research Association of Students in Pharmacy (GRASP) Conference, June 12th-14th, 2015. Mercer University, Atlanta, Georgia.
  125. Cedar H. A. Boakye, Punit Shah, Ravi Doddapaneni, Apurva Patel, Stephen Safe, Mandip Singh. Nurr1-targeted Delivery of inhibition of UVB-induced Oxidative Damage by a Diindolymethane Derivative for Skin Cancer Chemoprevention. 34th Graduate Research Association of Students in Pharmacy (GRASP) Conference, June 12th-14th, 2015. Mercer University, Atlanta, Georgia.
  126. Nusrat Chowdhury, Ketan Patel, Ravi Doddapaneni, Mandip Singh. Phosphofructokinase is a Novel Target for Lung Cancer Treatment. 34th Graduate Research Association of Students in Pharmacy (GRASP) Conference, June 12th-14th, 2015. Mercer University, Atlanta, Georgia.
  127. Ketan Patel, Cedar Boakye, Mandip Singh. Doxorubicin liposomes as an investigative model to study the permeation of nanocarrier into the skin. 34th Graduate Research Association of Students in Pharmacy (GRASP) Conference, June 12th-14th, 2015. Mercer University, Atlanta, Georgia. Best podium presentation award
  128. Cedar H. A. Boakye, Srujan Marepally, Apurva R. Patel, Chandraiah Godugu, Ravi Doddapaneni, Pinaki Desai, Mandip Singh. Co-transdermal delivery of dual siRNAs inhibits the IL23/TH17 signaling pathway and treats psoriatic-like plaque in mice. Florida A&M University, Tallahassee, FL, Graduate Student Appreciation Week, School of Graduate Studies, 2015.
  129. Arvind Bagde, Ketan Patel, Cedar Boakye, Mandip Singh. Quercetin nanogel for the prevention of skin photocarcinogenesis. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2015, Orlando, FL.
  130. Ketan Patel, Arvind Bagde, Cedar Boakye, Mandip Singh. Topical Delivery of Pemetrexed and siTNF&[alpha] Using Cationic Lipid Complexation with Urea Hydrogel: A Novel Synergistic Strategy for Psoriasis Treatment. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2015, Orlando, FL.
  131. Arvind Bagde, Ketan Patel, Cedar Boakye, Mandip Singh. Quercetin nanogel for the prevention of skin photocarcinogenesis. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2015, Orlando, FL.
  132. Ravi Doddapaneni, Ketan Patel, Nusrat Chowdhury, Mandip Singh. Noscapine chemosensitization enhanced tumor penetration of docetaxel PEGylated liposomes in triple-negative breast cancer. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2015, Orlando, FL.
  133. Cedar H. A. Boakye, Ketan Patel, Ravi Doddapaneni, Arvind Bagde, Mandip Singh. Simultaneous transdermal delivery of a tyrosine kinase inhibitor and IL36 siRNA via novel pyrrolidinium lipid nanocarriers treats psoriatic-like plaques in mice. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2015, Orlando, FL.
  134. Cedar H. A. Boakye, Ketan Patel, Punit P. Shah, Ravi Doddapaneni, Arvind Bagde, Nusrat Chowhury, Mandip Singh. Lipid-based delivery strategies for enhanced topical delivery of a novel diindolylmethane derivative for antioxidative therapeutic outcome. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2015, Orlando, FL.
  135. Ravi Doddapaneni, Ketan Patel, Nusrat Chowdhury, Mandip Singh. Chemosensitization enhances Docetaxel anticancer activity and tumor stroma disruption against Triple-Negative Breast Cancer. AACR Annual Meeting 2016
  136. Shallu Kutlehria, Gautam Behl, Ketan Patel, Ravi Doddapanenni, Mandip Sachdeva, Synthesis and Characterization of PEG-Cholecalciferol Nanomicelles and Determination of Molecular Pathway Involved in Overcoming Resistance in Triple-Negative Breast Cancer, GRASP 36th, FAMU, July,23,2016. BEST POSTER AWARD
  137. Shallu Kutlehria, Gautam Behl, Ketan Patel, Arvind Bagde, Synthesis and Characterization of Glutathione Responsive PEG-Cholecalciferol Nanomicelles for Ocular Delivery, Denver, November 13-17, 2016.
  138. Shallu Kutlehria, Arvind Bagde, Imran Vohra, Synthesis and Characterization of PEG-Cholecalciferol Nanomicelles for modified Ocular Delivery of Tacrolimus, GRASP 37th, North Carolina, May 2017.BEST POSTER AWARD
  139. Imran Vohra, Shallu Kutlehria, Mandip Sachdeva, Tacrolimus Nanoparticle Loaded Ion Sensitive In Situ Gelling System for Ocular Inflammation.American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2017, San Diego, CA.
  140. Arvind Bagde,Imran Vohra, Nilkumar Patel, Mandip Singh.Combination of UVB absorbing inorganic nanoparticle and Quercetin Nanogel for skin cancer chemoprevention. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2017, San Diego, CA.
  141. Arvind Bagde,Imran Vohra, Nilkumar Patel, Mandip Singh. Enhancement of bioavailability of ibuprofen by formulation of oral SLN using Hot Melt Extrusion (HME) technique. American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2017, San Diego, CA.
  142. Shallu Kutlehria, Imran Vohra, Arvind Bagde, Evaluation of PEG-Cholcecalciferol based nanomicelles for ocular delivery, American Association of Pharmaceutical Science (AAPS) Annual Meeting & Exposition 2017, San Diego, CA.
  143. Arindam Mondal, Aragaw Gebeyehu, Ebony Nottingham, Arvind Bagde, Subramanian Ramakrishnan, Arun k. Rishi, Mandip Singh, Combination of CDODA-Me, a glycyrrhetinic acid derivative and Erlotinib overcomes chemo-resistance in NSCLC PDX spheroids and 3D bio-printed cells, American Association for Cancer Research (AACR) Annual Meeting 2017, Washington, DC.
  144. Ebony Nottingham, Vasanth Sekar, Arindam Mondal, Mandip Sachdeva, The use of self nano-emulsifying drug delivery systems to improve the bioavailability of combination therapy and overcome erlotinib resistance in non-small cell lung cancer, American Association for Cancer Research (AACR) Annual Meeting 2017, Washington, DC.
  145. Nusrat Chowdhury, Ketan Patel, Vasanthakumar Sekar, Mandip Singh. Solid Dispersion of Tamoxifen Citrate with Resveratrol using Hot melt Extrusion, Graduate Student Appreciation Week 2017, Florida A&M University, Tallahassee, FL. Best Poster Award
  146. Nusrat Chowdhury, Ketan Patel, Vasanthakumar Sekar, Mandip Singh. Solid Dispersion of Tamoxifen Citrate with Resveratrol using Hot melt Extrusion, Statewide Graduate Student Research Symposium 2017, University of South Florida, Tampa, FL.
  147. Ebony Nottingham, Vasant Sekar, Stephen Safe, Arun Rishi, Arindam Mondal, Ravi Doddapaneni, Mandip Singh, The use of self nano-emulsifying drug delivery systems to improve the bioavailability of combination therapy and overcome erlotinib resistance in non-small cell lung cancer, 2018 Emerging Researchers National Conference, Washington, DC.
  148. Ebony Nottingham, Elizabeth Mazzio, Shallu Kutlehria, Ramesh Badisa, Mandip Sachdeva, The use of glycyrrhetinic acid derivatives to inhibit blebbishield emergency program pathogenesis overcoming erlotinib resistance in non-small cell lung cancer, 2018 Annual American Association for Cancer Research, Chicago, Illinois.
  149. Nusrat Chowdhury, Ketan Patel, Imran Vhora, Ravi Dossapaneni, Arindam Mondal, Shallu Kutlehria, Mandip Singh. Combination Therapy of Docetaxel and Fasentin in Overcoming Drug Resistance. FAMU & USF NanoBio Collaborative International Conference, January 2018. Honorable Mention Award
  150. Shallu Kutlehria, Imran Vohra, Arvind Bagde, Nusrat Chowdhury, Mandip Sachdeva, PEG-Cholecalciferol nanomicelles for Ocular drug delivery", USF - FAMU Nanobio Collaborative International Conference, 2018, Tampa, Florida. Best Poster Award.
  151. Paul Dinh, Shallu Kutlehria, Aragaw Gebeyehu, Coralin Nogues, Anirban Ganguly, Mandip Sachdeva. "3D Printed Cornea for in vitro Tissue Regeneration Model". Nanoflorida Conference October 2018, Florida Institute of Technology.
  152. Nilkumar Patel, Arvind Bagde, and Mandip Singh “Design and evaluation of Nabumetone solid lipid nanoparticles oral formulation using hot-melt extrusion (HME) technology as a continuous manufacturing process with Compritol® 888 ATO” Nanoflorida Conference October 2018, Florida Institute of Technology.
  153. Shallu Kutlehria, Imran Vohra, Arvind Bagde, Nusrat Chowdhury, Mandip Sachdeva, PEG-Cholecalciferol nanomicelles for Ocular drug delivery, USF - FAMU Nanobio Collaborative International Conference, 2018, Tampa, Florida.
  154. Shallu Kutlehria, Imran Vohra, Arvind Bagde, Nusrat Chowdhury, Mandip Sachdeva, PEG-VD3 based micelles for Ocular delivery, Graduate Appreciation Week, March 2018, FAMU.
  155. Aragaw Gebeyehu, Arindam Mondal, and Mandip Singh, Characterization and printability of Polysaccharide-based hydrogels to study the self-assembly of tumor spheroids, USF - FAMU Nanobio Collaborative International Conference, Jan 2018, Tampa, Florida.
  156. Aragaw Gebeyehu, Arindam Mondal, Rama krishnan Subramanian, Arun Rishi, Mandip Singh, Characterization and printability of Sodium alginate/gelatin hydrogel to study the self-assembly of tumor spheroids, Nanoflorida Conference Oct 2018, Florida Institute of Technology.
  157. Shallu Kutlehria, PEG-Cholecalciferol nanomicelles for ocular drug delivery, (ORAL PRESENTATION) USF - FAMU Nanobio Collaborative International Conference, Jan 2018, Tampa, Florida.
  158. Shallu Kutlehria, Paul Dinh, Aragaw Gebeheyu, Mandip Sachdeva, High‐Throughput 3D Bioprinting of Corneal Equivalents for a Realistic Blinking Eye Perfusion Model, 2019 AAPS Best Poster Award.
  159. Shallu Kutlehria, 3D printing of corneal equivalents: Florida Annual Meeting and Exposition (ORAL PRESENTATION) (FAME) 2019 by American chemical society (ACS), May 2019, Tampa Florida.
  160. Shallu Kutlehria, Targeted nanomicelles of Tacrolimus for ocular inflammation, (ORAL PRESENTATION) 4th Annual Vision Florida conference, Jan 2019, Tampa, Florida.
  161. Aragaw Gebeyehu, Arindam Mondal and Mandip Singh, Bioink formulation for 3D printed tumor culture model and anticancer drug screening in hydrogel-based tumor Microenvironment, Florida Annual Meeting and Exposition (FAME) 2019 by American chemical society (ACS), May 2019, Tampa Florida.
  162. Shallu Kutlehria, High-throughput 3D printing of corneal stromal equivalents. Presentation Distinction Award- 2019 Nanoflorida International Conference, Tampa (Oral Presentation).
  163. Shallu Kutlehria, Paul Dinh, Aragaw Gebeheyu, Mandip Singh High-throughput 3D bioprinting of corneal equivalents for realistic blinking eye perfusion model. AAPS 2019 Best Abstract Award Recipient, Travel Award Recipient. (Poster Presentation).
  164. Nilkumar Patel, Arvind bagde, Shallu Kutlehria, Arindam Mondal, David Meckes, Mandip Singh “Characterization of Extracellular vesicles from H460 tumor tissue after drug treatment” (Oral Presentation) Nanoflorida 2019 International Conference, November 15-17, 2019, University of South Florida.
  165. Peggy Arthur, Aragaw Gebeyehu, Nilkumar Patel, Sunil K. Surapaneni, Mandip Singh, Enhancement of Docetaxel efficacy in 3D lung cancer models. RCMI conference 2019, Bethesda, MD.
  166. Peggy Arthur, Aragaw Gebeyehu, Nilkumar Patel, Sunil K. Surapaneni, Mandip Singh, The anticancer efficacy of the combinational treatment of Docetaxel loaded Pegylated liposomes and a tumor-stromal disrupting agent in lung cancer. Nanoflorida 2019 International Conference, November 15-17, 2019, University of South Florida. (Oral &poster presentation)
  167. Conference paper accepted in Hilton Head 2020 conference: DLP 3D PRINTED “INTELLIGENT” MICRONEEDLE ARRAY (iµNA) FOR STIMULI RESPONSIVE RELEASE OF DRUGS AND ITS’ IN VITRO AND EX VIVO CHARACTERIZATION. Parker Arnett, Avra Kundu, Arvind Bagde, Nilab Azim, Mandip Sachdeva, and Swaminathan Rajaraman.
  168. Nottingham E, Mondal A, Surapaneni S, Sachdeva M. Combination Therapy in 3D NCSLC Tumor Model Overcomes Induced Drug Resistance. 2020 Annual Emerging Researchers Network, Washington, DC (February 2020)
  169. Ebony Nottingham, Arindam Mondal, Imran Vhora, Ketan Patel, Arun K. Rishi, Mandip Singh. Telmisartan synergistically enhances CFM 4.16 and Erlotinib combination therapy through enhanced tumor penetration in 3D printed models. AACR 2020.
  170. Ebony Nottingham, Elizabeth Mazzio, Shallu Kutlehria, Stephen Safe, Arun K Rishi, and Mandip Singh.Increased Initiation of Blebbishield Emergency Program Signaling as a Result of TGF-β Induced EMT Leads to Erlotinib Resistance in NSCLC. AACR 2020

 

CONTACT US

Mandip Singh Sachdeva, Ph.D.
Professor of Pharmaceutical Sciences
Pharmaceutics Section Leader 
Editor in Chief, Critical Reviews in Therapeutic Drug Carrier Systems
Dyson Pharmacy Building RM#021

Florida A&M University
College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health 
Tallahassee, FL 32307

Phone: 850-561-2790
Fax: 850-599-3818
mandip.sachdeva@famu.edu