Tiffany Wilson Ardley, Ph.D.

Director, B.S. Pharmaceutical Science Program and Assistant Professor Pharmaceutical Sciences
LOCATION: East Wing Pharmacy Building Suite # G-134D
EMAIL: tiffany.ardley@famu.edu
PHONE: 850-599-3774

EDUCATION
Biosketch

Tiffany Wilson Ardley, Ph.D., serves as the assistant professor, Basic Pharmaceutical Sciences, and as the director of the B.S. Pharmaceutical Sciences Program.

Dr. Ardley is a native of Tallahassee and attended FAMU High School (now FAMU DRS) from 1st through 12th grades.  She came to FAMU as a Presidential Scholar and majored in Biology and later obtained the MS and Ph.D. degrees in the College of Pharmacy & Pharmaceutical Sciences with an emphasis in Medicinal Chemistry.  She completed a postdoctoral fellowship at Howard University where she focused on the drug design and development of enaminone analogs.  During that postdoctoral experience, she was able to make structural modifications that produced compounds that were very effective in preventing seizures in animal models.   Her current research has yielded tetrahydropyridine derivatives that have been shown to have anti-inflammatory activity, which has prevented the growth of some breast cancer cell lines and those that have been shown to be inhibitors of the growth of T-cell and B-cell lymphomas. In addition to publications, she is currently filing a patent on a tetrahydropyridine derivative found to be very effective in inhibiting the growth of some breast cancer cell lines.  In addition to drug discovery research, she is the Co-PI of the third cycle of funding of a U.S. Department of Education Minority Science and Engineering Improvement Program grant that gets underrepresented high school students trained in STEM areas.  Additional STEM grants have been awarded in the Fall of 2019, totaling over 2.1 million dollars.  In 2017, she was very instrumental in the launching of the Bachelor of Science in Pharmaceutical Sciences program which is the only one at a College of Pharmacy at an HBCU.

Dr. Ardley has served on numerous division, college, and university committees.  She is the immediate past Secretary and is also the current Vice President of the FAMU Faculty Senate.  She also serves as the Primary Advisor to the Beta Alpha Chapter of Delta Sigma Theta Sorority, Inc. at FAMU.  In the community she is on the Board of Directors for PACE Center for Girls, a position she has held for over eight years.

Areas of Expertise
  • Medicinal Chemistry

Research Interest
  • Drug design and development to treat Breast Cancer

  • Prostate Cancer and Inflammation

  • Effectiveness of exposure to STEM on high school students

Selective Publications
  • Henderson ED, Gangapuram M, Eyunni SV, Redda KK, Wilson-Ardley T. Design, Synthesis and Evaluation of Novel N-Substituted-[Benzoylamino]-5-Ethyl1,2,3,6-Tetrahydropyridines as Potential Anti-Cancer Agents. Madridge J Pharm Res. 2019; 3(1): 52-59. doi: 10.18689/mjpr-1000109

  • Clark II, C.J., Ardley, T.W., and Black, J.T. “The Program of Excellence in STEM: Involvement of Traditionally Underrepresented Students in STEM Education Through Research and Mentoring at Florida A&M University”, Proceedings 5th IEEE Integrated STEM Conference, Princeton University; Princeton, NJ; March 7, 2015; pp. 164-168.

  • Yasmeen M. Nkrumah-Elie, Alicia M. Hudson, Equar Taka, Ramesh Badisa, David Bauer, Shanalee S. Gallimore, Bridg’ette Israel, Tiffany Ardley, Ebenezer Oriaku, Ronald D. Thomas*, Selina F. Darling-Reed; The attenuation of benzo(a)pyrene-induced carcinogenic insults by diallyl disulfide (DADS) in MCF-10A cells. Nutrition and Cancer: An International Journal, 64(7); 1112-21(2012)

  • Mohammad A. Ghafari, Tiffany W. Ardley, Madhavi Gangapuram and Kinfe K. Redda. The synthesis of n-Substituted Carbonylamino-1,2,3,6-Tetrahydropyridines as Potential Anti-inflammatory Agents. Synthetic Communications 41:17, 2615-2623, June 29 (2011). To link to this article: http://dx.doi.org/10.1080/00397911.2010.515335.

  • Bereket Mochona, Laine Le, Madhavi Gangapuram, Nelly Mateeva, Tiffany W. Ardley and Kinfe K. Redda. Synthesis of 2-(N-Benzylpyrrolyl)-benzimidazoles as Potential Anti-inflammatory Agents. Journal of Heterocyclic Chemistry 47(6): 1367-1371, November 1 (2010).

  • Ivan O. Edafiogho, Samuel B. Kombian, Kettireddy V.V. Anathalaskshmi, Noha N. Salama, Natalie D. Eddington, Tiffany L. Wilson, Mariano S. Alexander, Patrice L. Jackson, Clive D. Hanson, K. R. Scott. Mini Review – Enaminones: Exploring Additional Therapeutic Activities. Journal of Pharmaceutical Sciences, Oct;96(10):2509-3, (2007)DOI 10.1002/jps.20967.

  • Tiffany L. Wilson, Patrice L. Jackson, Clive D. Hanson, Z. Xue, Natalie D. Eddington and Kenneth R. Scott. QSAR of The Anticonvulsant Enaminones; Molecular Modeling Aspects and Other Assessments. Medicinal Chemistry, 1(4), 371-381 (2005).

  • Noah Nabil Salama, Natalie D. Eddington, Debra Payne, Tiffany L. Wilson and K.R. Scott. “ Multidrug Resistance and Anticonvulsants: New Studies with Some Enaminones.” Curr. Med. Chem., 11(15), 2093-2103 (2004).

  • T. Wilson and K. Redda, “Synthesis and Anti-inflammatory Activity Determinations of Some N-[Substituted Benzoyl(phenylsulfonyl)amino] -5-Ethyl-1,2,3,6-tetrahydropyridines”, Med. Chem. Res.,12 (2), 69-86 (2003).

  • T. Wilson, U.C. Unubogu, R. Kode, K.K. Redda. “The Pharmacological Evaluations of Some N [Pyridyl(phenyl)carbonylamino] hydroxypropyl-1,2,3,6-tetrahydropyridines as Potential anti-inflammatory agents.” Int. Journal of Drugs Under Experimental & Clinical Research XXIV(4) 165-172 (1998).